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Overview

Uniprot IDA0A5G2QGB3
Protein NameJunctional adhesion molecule C
Gene NameJAM3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
87 GRAELLGKTSLKIWN

Function

Promotes chemotaxis of vascular endothelial cells and stimulates angiogenesis

Protein Sequence

10 IRVVSSLILL 20 FFFPSGCLTG 30 AVNLKSSNRN 40 PVVQEFESVE 50 LSCIITDSQT 60 NDPRIEWKKI 70 QDEQTSYVFF 80 DNKIQGDLTG 90 RAELLGKTSL 100 KIWNVTRTDS 110 ALYRCEVVAR 120 NDRKEIDEIV 130 IELTVQVKPV 140 PPACRVPRAV 150 PVGKAATLSC 160 QEGEGYPRPH 170 YSWYRNDVPL 180 PTDSRANPRF 190 RNSSFLLNPE 200 TGTLVFNAVH 210 KEDSGQYYCI 220 ASNDAGSARC 230 EEQDMEVYDL 240 NISGIIGGVL 250 VVLTVLALIT 260 AGICCAYRRG 270 YFINNKQNGE 280 SYKNPGKPDG 290 VNYIRTDEEV 300 RSRVRSDLTK DT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005923 bicellular tight junction
Cellular Component GO:0030057 desmosome
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0042803 protein homodimerization activity
Biological Process GO:0007155 cell adhesion
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0048731 system development

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.