Search Results
Overview
| Uniprot ID | A0A5G2QH97 |
|---|---|
| Protein Name | Non-selective voltage-gated ion channel VDAC3 |
| Gene Name | VDAC3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 64 | GNLETKYKICDYGLT |
Function
Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations. Involved in male fertility and sperm mitochondrial sheath formation
Protein Sequence
10
MCNTPTYCDL
20
GKAAKDVFNK
30
GYGFGMVKID
40
LRTKSCSGVM
50
EFSTSGHAYT
60
DTGKASGNLE
70
TKYKICDYGL
80
TFTQKWNTDN
90
TLGTEISLEN
100
KLAEGLKLTL
110
DTIFVPNTGK
120
KSGKLKASYK
130
RECFSIGSNV
140
DIDFAGPTIY
150
GWAVLALEGW
160
LAGYQMSFDT
170
AKSKLSQNNF
180
ALGYKAADFQ
190
LHTHVNDGTE
200
FGGSIYQKVN
210
EKIETSINLA
220
WTAGSNNTRF
230
GIAAKYKLDC
240
RTSLSAKVNN
250
ASLIGLGYTQ
260
TLRPGVKLTL
270
SALIDGKNFS
280
AGGHKVGLGF
ELEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0046930 | pore complex |
| Molecular Function | GO:0000166 | nucleotide binding |
| Molecular Function | GO:0015288 | porin activity |
| Molecular Function | GO:0008308 | voltage-gated monoatomic anion channel activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.