Search Results
Overview
| Uniprot ID | A0A5G2QHA3 |
|---|---|
| Protein Name | Wiskott-Aldrich syndrome protein family member |
| Gene Name | WASF2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 71 | RVDRLQVKVTQLDPK |
Function
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex
Protein Sequence
10
MQTAQALEGM
20
FLSPRASSAC
30
SLNHLRGVGD
40
GVWEVGSKYA
50
EDIFGELFTQ
60
ANTFASRVSS
70
LAERVDRLQV
80
KVTQLDPKEE
90
EVSLQGINTR
100
KAFRSSTVQD
110
QKLFDRNSLP
120
IPVLETYNTC
130
DTPPPLNNLT
140
PYRDDGKEAL
150
KFYTDPSYFF
160
DLWKEKMLQD
170
TKDIMKEKRK
180
HRKEKKDNPN
190
RGNVNPRKIK
200
TRKEEWEKMK
210
MGQEFVESKE
220
KLGPSGYPPT
230
LVYQNGSVGS
240
VENVDASSYP
250
PPPQSDSTSP
260
PSPSFSEDSL
270
PPPPAEFSYP
280
ADSNQRGSGL
290
AGPKRSSVVS
300
PSHPPPAPPL
310
GSPPGPKPGF
320
APPPAPPPPP
330
PMMSTPPPPP
340
PGGFGSSGTP
350
PPPSPPSFPP
360
HPDFAAPPPP
370
PPPPAADYST
380
LPPPPLSQPA
390
GGAPPPPPPP
400
PPPGPPPPPF
410
SGTDGQPAAP
420
PPLSDTTKPK
430
SSLPPVSDAR
440
SDLLSAIRQG
450
KILVVEPGSW
NLVFLQLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Molecular Function | GO:0003779 | actin binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.