Search Results

Overview

Uniprot ID	A0A5G2QI99
Protein Name	Long-chain-fatty-acid--CoA ligase
Gene Name	ACSL1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
494	IQSSLGGKVRLMVTG

Function

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation

Protein Sequence

10 MMQAHELFRY 20 FRMPELVDFQ 30 QYVRTLPTNT 40 LMGFGAFAAL 50 TTFWYATRPR 60 ALKPPCDLAM 70 QSVEVAGSDG 80 ARRSAILDSD 90 EPLAYFYDDV 100 RTLYEGFQRG 110 IRVSNNGPCL 120 GSRKPDQPYE 130 WLSYKQCPCC 140 YLGQAAAQEH 150 REPPAVFPAR 160 PSRKGLSAAG 170 PVTPWHLGTW 180 RSPCVSAAEV 190 GVSQGMCVRG 200 HLQEPQNQVE 210 DMSECVGSAL 220 IHKGFKAGPE 230 NFVGIFAQNR 240 PEWVIIEQGC 250 FAYSMVVVPL 260 YDTLGTEAIT 270 YIINKGELSL 280 VFVDKPEKAN 290 LLLEGVENKL 300 IPGLKTIILM 310 DSYGIDLLER 320 GKKCGVEIMS 330 MKALEVSHPA 340 PPAPEDLAVI 350 CFTSGTTGNP 360 KGAMITHRNV 370 VSDCSAFVKV 380 TEKTFSPSSD 390 DTLISFLPLA 400 HMFERVVECV 410 MLCHGAKIGF 420 FQGDIRLLMD 430 DLKALQPTIF 440 PVVPRLLNRM 450 FDRIFGQANT 460 TLKRWLLDFA 470 SKRKEAELRS 480 GIIRNNSLWD 490 KLIFHKIQSS 500 LGGKVRLMVT 510 GAAPVSATVL 520 TFLRAALGCQ 530 FYEGYGQTEC 540 TAGCSLTVPG 550 DWTAGHVGAP 560 MPCSLIKLVD 570 VEEMNYLAAK 580 GEGEVCVKGP 590 NVFQGYLKDP 600 AKTAEALDKD 610 GWLHTGDIGK 620 WLPNGTLKII 630 DRKKHIFKLA 640 QGEYIAPEKI 650 ENIYLRSEPV 660 AQVFVHGESL 670 QAFLIAIVVP 680 DVETLGHWAQ 690 KRGFVGSFEE 700 LCRNKDVKKA 710 ILEDMLRLGR 720 DAGLKSFEQV 730 RGISLHPELF 740 SIDNGLLTPT 750 MKAKRPELRN 760 YFRSQIDELY STVKV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0005741	mitochondrial outer membrane
Molecular Function	GO:0047676	arachidonate-CoA ligase activity
Molecular Function	GO:0005524	ATP binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.