Search Results
Overview
| Uniprot ID | A0A5G2QIC3 |
|---|---|
| Protein Name | Ubiquitin carboxyl-terminal hydrolase |
| Gene Name | USP14 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 246 | SEEEEVTKGKENQLQ |
| 270 | KYLFTGLKLRLQEEI |
| 292 | QRNALYIKSSKISRL |
| 321 | EKESVNAKVLKDVKF |
| 366 | KKVNQQPKASDKKSS |
| 420 | GHYVSWVKRKQDEWI |
| 68 | DDDWGNIKIKNGMTL |
Function
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes
Protein Sequence
10
FPLKKNYGLF
20
AVTVKWGKEK
30
FEGVELNTDE
40
PPMVFKAQLF
50
ALTGVQPARQ
60
KVMVKGGTLK
70
DDDWGNIKIK
80
NGMTLLMMGS
90
ADALPEEPSA
100
KTVFVEDMTE
110
EQLASAMELP
120
CGLTNLGNTC
130
YMNATVQCIR
140
SVPELKDALK
150
RYAGALRASG
160
EMASAQYITA
170
ALRDLFDSMD
180
KTSSSIPPII
190
LLQFLHMAFP
200
QFAEKGEQGQ
210
YLQQGSNPRP
220
HGCWLDSEPS
230
IVCWQISYLL
240
LQSMKCTESE
250
EEEVTKGKEN
260
QLQLSCFINQ
270
EVKYLFTGLK
280
LRLQEEITKQ
290
SPTLQRNALY
300
IKSSKISRLP
310
AYLTIQMVRF
320
FYKEKESVNA
330
KVLKDVKFPL
340
MLDVYELCTP
350
ELQEKMVSFR
360
SKFKDLEDKK
370
VNQQPKASDK
380
KSSPQKEVKY
390
EPFSFADDIG
400
SNNCGYYDLQ
410
AVLTHQGRSS
420
SSGHYVSWVK
430
RKQDEWIKFD
440
DDKVSIVTPE
450
DILRLSGGGD
460
WHIAYVLLYG
470
PRRVEIMEEE
SE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000502 | proteasome complex |
| Molecular Function | GO:0004843 | cysteine-type deubiquitinase activity |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0016579 | protein deubiquitination |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.