Search Results
Overview
| Uniprot ID | A0A5G2QJ86 |
|---|---|
| Protein Name | mRNA cap guanine-N(7) methyltransferase |
| Gene Name | RNMT |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 128 | DGTQKKRKIELEDVP |
| 16 | ECEKLSLKEAKTSID |
| 271 | SKELLIDKFRDPEMC |
| 46 | PGTRLSEKAPTCGLV |
| 60 | VGTPKKRKMAFEDDL |
| 81 | CGEDTPSKKRKLDAG |
| 84 | DTPSKKRKLDAGIVP |
Function
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC
Protein Sequence
10
MENSAKAEEC
20
EKLSLKEAKT
30
SIDSETESSF
40
SIDENTTSPG
50
TRLSEKAPTC
60
GLVGTPKKRK
70
MAFEDDLVKE
80
SSSCGEDTPS
90
KKRKLDAGIV
100
PEEKGSGDDE
110
GISRKRRMES
120
DGFTKDESTG
130
DGTQKKRKIE
140
LEDVPEKRKN
150
LEEGHSSAVA
160
AHYNELQEVG
170
LEKRSQSRIF
180
YLRNFNNWMK
190
SVLIGEFLEK
200
VRQKKKRDIT
210
VLDLGCGKGG
220
DLLKWKKGRI
230
DKLVCTDIAD
240
VSVKQCQQRY
250
EDMKNRCRDN
260
EYIFSAEFIT
270
ADCSKELLID
280
KFRDPEMCFD
290
ICSCQFVCHY
300
SFESYEQADI
310
MLRNACERLS
320
PGGYFIGTTP
330
NSFELIRRLE
340
ASETESFGNE
350
IYTVKFQKKG
360
DYPLFGCKYD
370
FNLEGVVDVP
380
EFLVYFPLLN
390
EMAKKYNMKL
400
VYQKTFLEFY
410
EEKIKNNENK
420
MLLKRMQALE
430
PYPASENSRL
440
ASEKADDYEH
450
AAKYMKNSQV
460
RLPLGTLSKS
470
EWEATSIYLV
FAFEKQQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0160130 | mRNA cap methyltransferase RNMT:RAMAC complex |
| Cellular Component | GO:0031533 | mRNA capping enzyme complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0043235 | receptor complex |
| Molecular Function | GO:0004482 | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006370 | 7-methylguanosine mRNA capping |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.