Search Results
Overview
| Uniprot ID | A0A5G2QKD9 |
|---|---|
| Protein Name | Thioredoxin-dependent peroxide reductase, mitochondrial |
| Gene Name | PRDX3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 245 | TPDSPTIKPHPTDSK |
| 95 | ELSLDDYKGKYLVLF |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Required for the maintenance of physical strength
Protein Sequence
10
LFRAAPAAYG
20
SSQAGVIRHV
30
SAVPWGISAS
40
AALRPAPSRR
50
TCLTSVLWSG
60
SSQAKFAFST
70
SSSHHSPAVT
80
QHAPYFKGTA
90
VVNGEFKELS
100
LDDYKGKYLV
110
LFFYPLDFTF
120
VCPTEIIAFS
130
DKANEFHDVN
140
CEVVAVSVDS
150
HFSHLAWINT
160
PRKNGGLGHM
170
NIALLSDLTK
180
QISRDYGVLL
190
EGPGLALRGL
200
FIIDPNGVIK
210
HLSVNDLPVG
220
RSVEETLRLV
230
KAFQFVETHG
240
EVCPANWTPD
250
SPTIKPHPTD
260
SKEYFEKVHQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0140824 | thioredoxin-dependent peroxiredoxin activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.