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Overview

Uniprot IDA0A5G2QKY4
Protein NameDynein light intermediate chain
Gene NameDYNC1LI1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
269 KLQSLLAKQPPTAAG
63 VSTRSRSKLPAGKNV

Function

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes

Protein Sequence

10 MAAVGRVGSF 20 GSSPPGLVST 30 YTGGPLANEL 40 TSGNGGAATG 50 DDEDGQNLWS 60 CILSEVSTRS 70 RSKLPAGKNV 80 LLLVIRDFQE 90 YVEPGEDFPA 100 SPQRRNTVSQ 110 EDKDDSVVLP 120 LGADTLTQNL 130 GIPVLVVCTK 140 CDAISVLEKE 150 HDYRDEHFDF 160 IQSHIRKFCL 170 QYGAALIYTS 180 VKENKNIDLV 190 YKYIVQKLYG 200 FPYKIPAVVV 210 EKDAVFIPAG 220 WDNDKKIGIL 230 HENFQTLKAE 240 DNFEDIITKP 250 PVRKFVHEKE 260 IVAEDDQVFL 270 MKLQSLLAKQ 280 PPTAAGRPVD 290 ASPRVPGGSP 300 RTPNRSVSSN 310 VASVSPIPAG 320 SKKIDPNMKA 330 GATSEGVLAN 340 FFNSLLSKKT 350 GSPGGPAVGG 360 GSPGGGAGGG 370 SSGLPPSAKK 380 SGQKPVLSDV 390 HAELDRIARK 400 PVTVSSTTPT SPTEGEAS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005868 cytoplasmic dynein complex
Cellular Component GO:0005874 microtubule
Molecular Function GO:0005524 ATP binding
Biological Process GO:0007018 microtubule-based movement

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.