Search Results
Overview
| Uniprot ID | A0A5G2QLA4 |
|---|---|
| Protein Name | Disintegrin and metalloproteinase domain-containing protein 17 |
| Gene Name | ADAM17 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 523 | DRNSPCCKNCQFETA |
Function
No function data available.
Protein Sequence
10
MRQCALFLTS
20
LVPIVLAPRP
30
PDEPGFGSPQ
40
RLEKLDSLLS
50
DYDILSLSSI
60
RQHSVRKRDL
70
QASTHLETLL
80
TFSALNRHFK
90
LYLTSSTERF
100
SQNFKVVVVD
110
GEDESEYPVK
120
WQDFFSGHVV
130
GEPDSRVLAH
140
IGDDDITVRI
150
NTDGAEYNIE
160
PLWRLINDTK
170
DKRVLVYKSE
180
DIKNVSRLQS
190
PKVCGYIKAD
200
NEELLPKGLV
210
DREPPDELVH
220
RVKRRADPNP
230
LRNTCKLLVV
240
ADHRFYKYMG
250
RGEESTTTNY
260
LIELIDRVDD
270
IYRNTSWDNA
280
GFKGYGIQIE
290
QIRILKSPQE
300
VKPGERHYNM
310
AKSYPNEEKD
320
AWDVKMLLEQ
330
FSFDIAEEAS
340
KVCLAHLFTY
350
QDFDMGTLGL
360
AYVGSPRANS
370
HGGVCPKAYY
380
SPIGKKNIYL
390
NSGLTSTKNY
400
GKTILTKEAD
410
LVTTHELGHN
420
FGAEHDPDGL
430
AECAPNEDQG
440
GKYVMYPIAV
450
SGDHENNKMF
460
SNCSKQSIYK
470
TIESKAQECF
480
QERSNKVCGN
490
SRVDEGEECD
500
PGIMYLNNDT
510
CCNSDCTLRP
520
GVQCSDRNSP
530
CCKNCQFETA
540
QKKCQEAINA
550
TCKGVSYCTE
560
TDHSCKVCCR
570
APSGRCLPYV
580
DAEQKNLFLR
590
KGKPCTVGFC
600
DMNGKCEKRV
610
QDVIERFWEF
620
IDKLSINTFG
630
KFLADNIVGS
640
VLVFSLMLWI
650
PVSILVHCVD
660
KKLDKQYESL
670
SLLHPSNVEM
680
LSSMDSASVR
690
IIKPFPAPQT
700
PGRLQPLQPG
710
PVLPSAPSVP
720
VAPKLDHQRM
730
DTIQEDPSTD
740
SHVDEDGFEK
750
DPFPNSSAAA
760
KSFEDLTDHP
770
VTRSEKASSF
780
KLQRQSRVDS
KETEC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Molecular Function | GO:0030165 | PDZ domain binding |
| Molecular Function | GO:0043120 | tumor necrosis factor binding |
| Biological Process | GO:0030183 | B cell differentiation |
| Biological Process | GO:0033627 | cell adhesion mediated by integrin |
| Biological Process | GO:0071403 | cellular response to high density lipoprotein particle stimulus |
| Biological Process | GO:0071679 | commissural neuron axon guidance |
| Biological Process | GO:0140447 | cytokine precursor processing |
| Biological Process | GO:0050830 | defense response to Gram-positive bacterium |
| Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway |
| Biological Process | GO:0002467 | germinal center formation |
| Biological Process | GO:0006509 | membrane protein ectodomain proteolysis |
| Biological Process | GO:0120163 | negative regulation of cold-induced thermogenesis |
| Biological Process | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process | GO:0007220 | Notch receptor processing |
| Biological Process | GO:0007219 | Notch signaling pathway |
| Biological Process | GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0043536 | positive regulation of blood vessel endothelial cell migration |
| Biological Process | GO:0030307 | positive regulation of cell growth |
| Biological Process | GO:0032722 | positive regulation of chemokine production |
| Biological Process | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway |
| Biological Process | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0010820 | positive regulation of T cell chemotaxis |
| Biological Process | GO:0032760 | positive regulation of tumor necrosis factor production |
| Biological Process | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway |
| Biological Process | GO:1905564 | positive regulation of vascular endothelial cell proliferation |
| Biological Process | GO:0002532 | production of molecular mediator involved in inflammatory response |
| Biological Process | GO:0033025 | regulation of mast cell apoptotic process |
| Biological Process | GO:0001666 | response to hypoxia |
| Biological Process | GO:0032496 | response to lipopolysaccharide |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
| Biological Process | GO:0023061 | signal release |
| Biological Process | GO:0048536 | spleen development |
| Biological Process | GO:0033077 | T cell differentiation in thymus |
| Biological Process | GO:0035313 | wound healing, spreading of epidermal cells |
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005911 | cell-cell junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0005178 | integrin binding |
| Molecular Function | GO:0005138 | interleukin-6 receptor binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0070573 | metallodipeptidase activity |
| Molecular Function | GO:0004222 | metalloendopeptidase activity |
| Molecular Function | GO:1902945 | metalloendopeptidase activity involved in amyloid precursor protein catabolic process |
| Molecular Function | GO:0005112 | Notch binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.