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Overview

Uniprot IDA0A5G2QLN5
Protein NameNucleoporin NDC1
Gene NameNDC1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
640 FAFRASLKTAIYRIT

Function

Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane

Protein Sequence

10 MATAASRPCA 20 GGSRDILWRV 30 LGWRIVTSIV 40 WSVLLLPICT 50 TVYVLVSSID 60 LFHPIQWLSD 70 SFSGLYSSYI 80 IFYLLLLSVV 90 IVIISIFNVE 100 FYTVVPSIPC 110 SRLALIGKII 120 HPQQLMHSFV 130 HAAMGMMMAW 140 CAAVITKGPY 150 SFLVVPCTGT 160 ESLDGPAAQT 170 CLNEYHLFFL 180 LAGAFMGYSY 190 SLLYFINNMN 200 YLPFPIIQQY 210 KFLRFRRSLL 220 LLVKHSCVES 230 LFLLRNFCIV 240 YYFLGHIPKA 250 WISTAMDLQL 260 DEQFHRPLDT 270 VSGLLNLSLL 280 YHVWLCGVFL 290 LMTWYISWIL 300 FKIYATEAHL 310 FPVQPPFSEE 320 SDECLPKVLN 330 SSPPLIIKYL 340 ALQDLMLLSQ 350 YSPSRRQEVF 360 SLSQPGGHPH 370 NWTAISRECL 380 NLLNDMTQKL 390 VLYQEAAATN 400 GRVMSSSYAG 410 EPKQLDSPEE 420 TTFQTPKPSQ 430 VPRPSVPSLI 440 KTSLFSSKLS 450 TPDVASPLAT 460 PFGSSVVNRM 470 AGIFDVNTCY 480 GSPQSPQLTR 490 RGPRLWTSAA 500 DQQMTEFSNP 510 SPSTSVSAEG 520 KTVRQPSVIY 530 SWIQNKREQI 540 KNFLSKRVLI 550 MYFFSKHPEA 560 SIQAVFSDAQ 570 MHIWALEGLS 580 HLVAASFTED 590 RFGVVQTTLP 600 AILNTLLTLQ 610 EAVDKYFKLP 620 HASSKPPRIS 630 GSLVDTSYKT 640 LRFAFRASLK 650 TAIYRITTTF 660 GEHLNAVQAS 670 AEHQKRLQQF LEFKE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0031965 nuclear membrane
Cellular Component GO:0070762 nuclear pore transmembrane ring
Molecular Function GO:0030674 protein-macromolecule adaptor activity
Molecular Function GO:0017056 structural constituent of nuclear pore
Biological Process GO:0051028 mRNA transport
Biological Process GO:0051292 nuclear pore complex assembly
Biological Process GO:0051664 nuclear pore localization
Biological Process GO:0006999 nuclear pore organization
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.