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Overview

Uniprot ID	A0A5G2QM65
Protein Name	Electron transfer flavoprotein-ubiquinone oxidoreductase
Gene Name	ETFDH
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
212	TNDVGIQKDGAPKTT
243	GCHGHLAKQLYKKFD
273	ELWVIDEKKWKPGRV
486	GSDSDQLKPAKDCTP
579	AQNCVHCKTCDIKDP
77	LSAATRLKQLAAQHE
85	QLAAQHEKDLRVCLV

Function

Accepts electrons from ETF and reduces ubiquinone

Protein Sequence

10 AYQCFHALKI 20 KKNYLPLCAT 30 RWSSTCKVPR 40 ITTHYTIYPR 50 DQDKRWEGVN 60 MERFAEEADV 70 VIVGAGPAGL 80 SAATRLKQLA 90 AQHEKDLRVC 100 LVEKAAQIGA 110 HTLSGACLDP 120 RAFEELFPDW 130 KEKGAPLNTP 140 VTEDRFGILT 150 EKYRIPVPIL 160 PGLPMNNHGN 170 YVVRLGHLVS 180 WMGEQAEALG 190 VEVYPGYAAA 200 EILFHEDGSV 210 KGIATNDVGI 220 QKDGAPKTTF 230 ERGLELHAKV 240 TIFAEGCHGH 250 LAKQLYKKFD 260 LRANCEPQTY 270 GIGLKELWVI 280 DEKKWKPGRV 290 DHTVGWPLDR 300 HTYGGSFLYH 310 LNEGEPLLAL 320 GFVVGLDYQN 330 PYLSPFREFQ 340 RWKHHPSIKP 350 TLEGGKRIAY 360 GARALNEGGF 370 QSIPKLTFPG 380 GLLIGCSPGF 390 MNVPKIKGTH 400 TAMKSGILAA 410 ESIFNQLTSE 420 NLQSKTIGLH 430 VTEYEDNLKN 440 SWVWKELYSV 450 RNIRPSCHGI 460 LGVYGGMIYT 470 GIFYWIFRGM 480 EPWTLKHKGS 490 DSDQLKPAKD 500 CTPIEYPKPD 510 GQISFDLLSS 520 VALSGTNHEH 530 DQPAHLTLKD 540 DSVPVNRNLS 550 IYDGPEQRFC 560 PAGVYEFVPL 570 EQGDGFRLQI 580 NAQNCVHCKT 590 CDIKDPSQNI 600 NWVVPEGGGG PAYNGM

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding
Molecular Function	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity
Molecular Function	GO:0046872	metal ion binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.