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Overview

Uniprot IDA0A5G2QPA7
Protein NameDNA repair protein Ku70
Gene NameXRCC6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
240 RETNEPVKTKTRTFN
274 NRQIVLEKEETEMLK
482 PDYNPEGKAPKRKQD
499 SCGSKRPKVELSEEE
518 ISEGTLGKLTVPTLK

Function

No function data available.

Protein Sequence

10 VKEARQKFCI 20 QSVYTNKIIS 30 SDRDLLAVVF 40 YGTKKDKNSV 50 NFKNIYVLQE 60 LDSPGAKRVQ 70 ELDRFKGQEG 80 TKYFQDLLGH 90 GSDYSLSEVL 100 WVCANLFSDV 110 QVKMSHKRIM 120 LFTNDDDPHG 130 NDSAKASRAR 140 TKAGDLRDTG 150 IFLDLMHLKK 160 PGGFDISLFY 170 RDIISVAEDE 180 DIGVHFEESH 190 KLEDLLRKVR 200 AKETRKRVLH 210 RLKLKLSKDV 220 ALTVGIYNLV 230 QKAYKPFPVR 240 LCRETNEPVK 250 TKTRTFNVNT 260 GSLLLPSDTK 270 RSQTYGNRQI 280 VLEKEETEML 290 KRFDEPGLIL 300 IGFKPLGMLK 310 RHHYVRPSLF 320 VYPEESLVNG 330 SSTLFTALLT 340 KCLEKEVMAV 350 CRYTPRKNLP 360 PYFVALMPQE 370 EELDDQKVQV 380 TPPGFQLVFL 390 PYADDKRKVP 400 FTEKIMANPE 410 QVDKMKAIVQ 420 KLRFKYRSDS 430 FENPVLQQHF 440 RNMEALALDL 450 MEPEQAVDLT 460 LPKAEAMAKR 470 LGSLVDEFKE 480 LVYPPDYNPE 490 GKAPKRKQDN 500 ESCGSKRPKV 510 ELSEEELKAH 520 ISEGTLGKLT 530 VPTLKEACRV 540 HGVKGGMKKQ 550 ELLDALTKHF QD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005694 chromosome
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0043564 Ku70:Ku80 complex
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0003684 damaged DNA binding
Molecular Function GO:0003678 DNA helicase activity
Molecular Function GO:0003690 double-stranded DNA binding
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0016829 lyase activity
Molecular Function GO:0042162 telomeric DNA binding
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0045087 innate immune response
Biological Process GO:0002684 positive regulation of immune system process
Biological Process GO:0010212 response to ionizing radiation
Biological Process GO:0000723 telomere maintenance

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.