Search Results

Overview

Uniprot IDA0A5G2QPB6
Protein NameNADH-cytochrome b5 reductase
Gene NameCYB5R3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
115 LVIKVYFKDTHPKFP
120 YFKDTHPKFPAGGKM
156 LVYQGKGKFAIRPDK
294 LERVGHPKERCFAF*
50 YPLRLIDKEVVNHDT

Function

Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor

Protein Sequence

10 MGAQLSTLGH 20 VVLSPVWFLY 30 SLLMKLFQRS 40 TPAITLENPD 50 IKYPLRLIDK 60 EVVNHDTRRF 70 RFALPSPQHV 80 LGLPVGQHIY 90 LSARIDGNLV 100 IRPYTPVSSD 110 DDKGFVDLVI 120 KVYFKDTHPK 130 FPAGGKMSQY 140 LESMKIGDTI 150 EFRGPNGLLV 160 YQGKGKFAIR 170 PDKKSSPVIK 180 TVKSVGMIAG 190 GTGITPMLQV 200 IRAIMKDPDD 210 HTVCHLLFAN 220 QTEKDMLRPE 230 LEELRNEHSA 240 RFKLWYTVDR 250 APEAWDYSQG 260 FVNEEMIRDH 270 LPPPEEEPLV 280 LMCGPPPMIQ 290 YACLPNLERV 300 GHPKERCFAF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0005811 lipid droplet
Cellular Component GO:0005741 mitochondrial outer membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:1903958 nitric-oxide synthase complex
Molecular Function GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H
Molecular Function GO:0090524 cytochrome-b5 reductase activity, acting on NADH
Molecular Function GO:0071949 FAD binding
Molecular Function GO:0050421 nitrite reductase (NO-forming) activity
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0006809 nitric oxide biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.