Search Results
Overview
| Uniprot ID | A0A5G2QPM3 |
|---|---|
| Protein Name | Polymerase delta-interacting protein 3 |
| Gene Name | POLDIP3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 143 | TPALKLTKTIQVPQQ |
| 318 | VAEVVFVKKDDAITA |
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex
Protein Sequence
10
MMDFIWNALH
20
YGFIWILNAR
30
PGVGGIRSRV
40
GIQQSLLSQP
50
ARTATFQQRF
60
DARQKIGLSD
70
ARLKLGVKDA
80
REKLLQKDAR
90
FRIKGKVQDA
100
REMLNSRKQQ
110
STVPQKPRQV
120
ADAREKISLK
130
RNSPAAFMSP
140
PIGTVTPALK
150
LTKTIQVPQQ
160
KAMAPVHAHP
170
AGMRINVVNN
180
HQAKQNLYDL
190
DEDDDVAPIP
200
SKQMKFVAPG
210
NFLHHVAGLS
220
SSKLSMSKAL
230
PLTKVVQNDA
240
YTAPALPSSV
250
RTKALTNMSR
260
TLVNKEEPPK
270
ELPPAEPVLS
280
PLEGTKMTVN
290
NLHPRVTEED
300
IVELFCVCGA
310
LKRARLVHPG
320
VAEVVFVKKD
330
DAITAYKKYN
340
NRCLDGQPMK
350
CNLHMNGNVI
360
TSDQPILLRL
370
SDSPSVKKES
380
ELPRRVNSAG
390
SSNPPAEVDP
400
DTILKALFKS
410
SGASVTTQPT
EFKIKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0016973 | poly(A)+ mRNA export from nucleus |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.