Search Results

Overview

Uniprot ID	A0A5G2QPV3
Protein Name	-
Gene Name	TMEM214
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
102	TVTNQNQKQGRFRSL
27	PGAGGSGKGGGGDRR

Function

Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress

Protein Sequence

10 MAAKTAGGGR 20 WEVVKKGRRP 30 GAGGSGKGGG 40 GDRRALGEAN 50 GVWKYDLTPP 60 IQTTSTLYER 70 GFEKIMKRQN 80 KEQVPPPAVE 90 PKKPATKKQT 100 KKGATVTNQN 110 QKQGRFRSLE 120 EALKALDVAA 130 LQKELDKSQS 140 VFSENPSVWL 150 KDLASYLNYK 160 LQTPTSEPTL 170 SQHTHGESLH 180 GYRICIQAIL 190 QDKPKIATTN 200 LGKFLELLRS 210 HQSRPAKCLT 220 IMWALGQAGF 230 ANLTEGLKVW 240 LRIMMPVLGI 250 RSLSPFAIAY 260 LDRLLLMHPN 270 LTKGFGMIGP 280 KDFFPLLDFA 290 YMPNNSLTPS 300 LQEQLCRLYP 310 RLKVLAFGAK 320 PESTLHTYFP 330 SFLSRATPGC 340 PPEMKKELLS 350 SLTECLTVDP 360 LSTSVWRQLY 370 PKHLPQSSLL 380 LEHLLKSWER 390 IPKKTQKSLQ 400 ETTQSFKLTN 410 QDLLRKGIDS 420 NQDAIACDTA 430 CTSLLQQARG 440 FRLPWARLLM 450 LVLVFAVGFL 460 CHDLRSHSSF 470 QASLSGRLLQ 480 SSGFLPAGQQ 490 ACTKIYSYSL 500 QGYSWLQESL 510 PAWGSHLLTT 520 ARPSLQLAWA 530 HTNATVRFLS 540 AHCASHLAWL 550 GDSLTSLSQR 560 LQIQLPDALN 570 QLLHSLRELL 580 LFLYQNVLLP 590 MWHLLLEALA 600 RAQEHCHEAC 610 RGEVTWDCVK 620 TQLSKAAHWT 630 WLCLQDVTVA 640 FLDWALAMIS QQ

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Biological Process	GO:0006915	apoptotic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.