Search Results
Overview
| Uniprot ID | A0A5G2QR34 |
|---|---|
| Protein Name | 6-phosphogluconate dehydrogenase, decarboxylating |
| Gene Name | PGD |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | RCRDLKAKGILFVGS |
| 248 | KFQDADGKHLLPKIR |
| 253 | DGKHLLPKIRDSAGQ |
| 294 | ARCLSSLKDERVQAS |
| 309 | KKLKGPQKIQFSGDK |
| 316 | KIQFSGDKKSFLEDI |
| 317 | IQFSGDKKSFLEDIR |
| 325 | SFLEDIRKALYASKI |
| 374 | IRSVFLGKIKDAFDR |
| 376 | SVFLGKIKDAFDRNP |
| 38 | AFNRTVSKVDDFLAN |
| 48 | DFLANEAKGTRVVGA |
Function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Protein Sequence
10
MAQADIALIG
20
LAVMGQNLIL
30
NMNDHGFVVC
40
AFNRTVSKVD
50
DFLANEAKGT
60
RVVGARSLEE
70
MVSMLKKPRR
80
IILLVKAGQA
90
VDDFIEKLVP
100
LLDTGDIIID
110
GGNSEYRDTT
120
RRCRDLKAKG
130
ILFVGSGVSG
140
GEEGARYGPS
150
LMPGGNREAW
160
PHLKEIFQSI
170
AAKVGTGEPC
180
CDWVGDEGAG
190
HFVKMVHNGI
200
EYGDMQLICE
210
AYHLMKDVLG
220
MEQHEMAKAF
230
EEWNKTELDS
240
FLIEITANIL
250
KFQDADGKHL
260
LPKIRDSAGQ
270
KGTGKWTAIS
280
ALEYGVPVTL
290
IGEAVFARCL
300
SSLKDERVQA
310
SKKLKGPQKI
320
QFSGDKKSFL
330
EDIRKALYAS
340
KIISYTQGFM
350
LLRQAAAEFG
360
WSLNYGGIAL
370
MWGGCIIRSV
380
FLGKIKDAFD
390
RNPGLQNLLL
400
DDFFKSAVED
410
CQDSWRRAVS
420
TGVQTGIPMP
430
CFTTALSFYD
440
GYRHEMLPAN
450
LIQAQRDYFG
460
AHTYELLAKP
470
GHFVHTNWTG
480
HGGSVSSSSY
NA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0050661 | NADP binding |
| Molecular Function | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity |
| Biological Process | GO:0019521 | D-gluconate metabolic process |
| Biological Process | GO:0009051 | pentose-phosphate shunt, oxidative branch |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.