Search Results
Overview
| Uniprot ID | A0A5G2QSU5 |
|---|---|
| Protein Name | Pyruvate dehydrogenase E1 component subunit beta |
| Gene Name | PDHB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 186 | PWSSEDAKGLIKSAI |
| 229 | DFLIPIGKAKIERQG |
| 356 | KDIIFAIKKTLNI** |
Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2
Protein Sequence
10
MAVVAGLVRR
20
PLEQVSGLLL
30
RRRFHRTAPA
40
ALQVTVRDAI
50
NQGMDEELER
60
DEKVFLLGEE
70
VAQYDGAYKV
80
SRGLWKKYGD
90
KRIIDTPISE
100
VSLSSGSRPL
110
RRHAGLRPIC
120
EFMTFNFSMQ
130
AIDQVINSAA
140
KTYYMSGGLQ
150
SVPIVFRGPN
160
GASAGVAAQH
170
SQCFAAWYGH
180
CPGLKVVSPW
190
SSEDAKGLIK
200
SAIRDNNPVV
210
VLENELMYGV
220
PFELPAEAQS
230
KDFLIPIGKA
240
KIERQGTHIT
250
IVSHSRPVGH
260
CLEAATVLSK
270
EGIECEVINM
280
RTIRPMDIET
290
IEASVMKTTH
300
LITVEGGWPQ
310
FGIGAEICAR
320
IMEGPAFNFL
330
DAPAVRVTGA
340
DVPMPYAKIL
350
EDNSVPQVKD
360
IIFAIKKTLN
I
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity |
| Biological Process | GO:0006006 | glucose metabolic process |
| Biological Process | GO:0006086 | pyruvate decarboxylation to acetyl-CoA |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.