Search Results
Overview
| Uniprot ID | A0A5G2QT56 |
|---|---|
| Protein Name | Pleckstrin |
| Gene Name | PLEK |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 305 | EFRGVIIKQGCLLKQ |
Function
Major protein kinase C substrate of platelets
Protein Sequence
10
MCIHFILKLF
20
KKVPAECHSP
30
LPLKAAFLAA
40
WARKCGSPAF
50
TLAKASLLPK
60
SCATDQRALE
70
NIKAQLFLLS
80
LQGSMFNTWK
90
PMWVILLEDG
100
IEFYKKKSDN
110
SPKGMIPLKG
120
STLTSPCQDF
130
GKRMFVFKIT
140
TTKQQDHFFQ
150
AAFLEERDGW
160
VRDIKKAIKC
170
IEGGQKFARK
180
STRRSIRLPE
190
TIDLGALYLS
200
MKDTEKGIKE
210
LNLEKDKKVF
220
NHCFTGNCVI
230
DWLLSNNSVR
240
NRQEGIMIAS
250
SLLNEGYLQP
260
AGDLSKSAVD
270
GTAENPFLDN
280
ADAFYYFPDS
290
GFFCEDNSSD
300
DDVILKEEFR
310
GVIIKQGCLL
320
KQGHRRKNWK
330
VRKFILREDP
340
AYLHYYDPAG
350
GEDPLGAIHL
360
RGCVVTSVES
370
NTDGRRSEEE
380
NLFEIITADE
390
VHYFLQAANP
400
KERTEWIKAI
QVASRTGK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0005080 | protein kinase C binding |
| Biological Process | GO:0030866 | cortical actin cytoskeleton organization |
| Biological Process | GO:0002244 | hematopoietic progenitor cell differentiation |
| Biological Process | GO:0043647 | inositol phosphate metabolic process |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0010920 | negative regulation of inositol phosphate biosynthetic process |
| Biological Process | GO:0070495 | negative regulation of thrombin-activated receptor signaling pathway |
| Biological Process | GO:0030845 | phospholipase C-inhibiting G protein-coupled receptor signaling pathway |
| Biological Process | GO:0002576 | platelet degranulation |
| Biological Process | GO:0032233 | positive regulation of actin filament bundle assembly |
| Biological Process | GO:0030836 | positive regulation of actin filament depolymerization |
| Biological Process | GO:0060305 | regulation of cell diameter |
| Biological Process | GO:0031529 | ruffle organization |
| Biological Process | GO:0070493 | thrombin-activated receptor signaling pathway |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0019211 | phosphatase activator activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.