Search Results
Overview
| Uniprot ID | A0A5G2QU20 |
|---|---|
| Protein Name | Pre-mRNA-processing factor 19 |
| Gene Name | PRPF19 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 117 | RVIARLTKEVTAARE |
| 177 | IIQKLQDKATVLTTE |
| 190 | TERKKRGKTVPEELV |
| 242 | ILTGGADKNVVVFDK |
| 259 | EQILATLKGHTKKVT |
| 59 | VAHPIRPKPPSATSI |
Function
Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome
Protein Sequence
10
MISNEVPEHP
20
CVSPVSNHVY
30
ERRLIEKYIA
40
ENGTDPINNQ
50
PLSEEQLIDI
60
KVAHPIRPKP
70
PSATSIPAIL
80
KALQDEWDAV
90
MLHSFTLRQQ
100
LQTTRQELSH
110
ALYQHDAACR
120
VIARLTKEVT
130
AAREALATLK
140
PQAGLIVPQA
150
VPSSQPTRLW
160
VVGAGEPMDL
170
GELVGMTPEI
180
IQKLQDKATV
190
LTTERKKRGK
200
TVPEELVKPE
210
ELSKYRQVAS
220
HVGLHSASIP
230
GILALDLCPS
240
DTNKILTGGA
250
DKNVVVFDKS
260
SEQILATLKG
270
HTKKVTSVVF
280
HPSQELVFSA
290
SPDATIRIWS
300
VPNASCVQVV
310
RAHESAVTGL
320
SLHATGDYLL
330
SSSDDQYWAF
340
SDIQTGRVLT
350
KVTDETSGCS
360
LTCAQFHPDG
370
LIFGTGTMDS
380
QIKIWDLKER
390
TNVANFPGHS
400
GPITSIAFSE
410
NGYYLATAAD
420
DSSVKLWDLR
430
KLKNFKTLQL
440
DNNFEVKSLI
450
FDQSGTYLAL
460
GGTDVQIYIC
470
KQWTEILHFT
480
EHSGVTTGVA
490
FGHHAKFIAS
500
TGMDRSLKFY
SL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0000974 | Prp19 complex |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0061630 | ubiquitin protein ligase activity |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0070534 | protein K63-linked ubiquitination |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.