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Overview

Uniprot IDA0A5G2QUA2
Protein NameProtein transport protein Sec31A
Gene NameSEC31A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1108 PTEKITKKPIPDEHL
111 SKIIAGDKEVVIAQN
1138 SATDPQTKRKLDDAS
1140 TDPQTKRKLDDASKR
206 RKNEPIIKVSDHSNR
441 VTEQEFLKRSDQLQQ
461 GFVSYCQKKIDASQT
462 FVSYCQKKIDASQTE
489 FEDDSRGKYLELLGY
621 TQKKYFAKSQSKITR
648 IVESCDLKNWREALA
71 SSSHRYHKLIWGPHK
803 PGHQESPKSPYERQQ

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Protein Sequence

10 MKLKEVDRTA 20 MQAWSPAQNH 30 PIYLATGTSA 40 QQLDATFSTS 50 ASLEIFELDL 60 SDPSLDMKSC 70 ATFSSSHRYH 80 KLIWGPHKMD 90 SQGNVSGVLI 100 AGGENGNTIL 110 YDPSKIIAGD 120 KEVVIAQNDK 130 HTGPVRALDV 140 NIFQTNLVAS 150 GANESEIYIW 160 DLNNFATPMT 170 PGAKTQPPED 180 ISCIAWNRQV 190 QHILASASPS 200 GRATVWDLRK 210 NEPIIKVSDH 220 SNRMHCSGLA 230 WHPDVATQMV 240 LASEDDRLPV 250 VQMWDLRFAS 260 SPLRVLENHA 270 RGILAIAWSM 280 ADPELLLTCG 290 KDAKILCSNP 300 NTGEVLYELP 310 TNTQWCFDIQ 320 WCPRNPAVLS 330 AASFDGRISV 340 YSIMGGSADG 350 LRQKQVDKLS 360 SSFGNLDPFG 370 TGQPLPPLQI 380 PQQTAQHSVV 390 LPLKKPPKWI 400 RRPVGASFSF 410 GGKLVTFASV 420 RAQPPQGAEP 430 QQPQQHHVLI 440 SQVVTEQEFL 450 KRSDQLQQVV 460 QSQGFVSYCQ 470 KKIDASQTEF 480 EKNVWSFLKV 490 NFEDDSRGKY 500 LELLGYRKED 510 LGKKIALALN 520 KVDGPDVALT 530 DSDQLAQSDG 540 EESPAAGEQL 550 LGERIKEEKQ 560 ESEFLPSAGG 570 TFNISVSGDI 580 DGLITQALLT 590 GDFESAVDLC 600 LHDNRMADAI 610 ILAIAGGQEL 620 LARTQKKYFA 630 KSQSKITRLI 640 TAVVMKDWKE 650 IVESCDLKNW 660 REALAAVLTY 670 AKPDEFSALC 680 DLLGTRLESE 690 GDSLLQTQAC 700 LCYICAGNVE 710 KLVACWTKAQ 720 DGSNPLSLQD 730 LIEKVVILRR 740 AVQLTQAVDT 750 NAVGVLLAEK 760 MSQYASLLAA 770 QGSIAAALAF 780 LPENTNQPNI 790 VQLRDRLCRA 800 QGDPAPGHQE 810 SPKSPYERQQ 820 LPKGRPGPVA 830 GHTQMPRVPA 840 QQYYPHGENP 850 PPPAFVMHGS 860 GHPNAGAPTP 870 LGHVHTQVPP 880 YPQPQPYQPA 890 QQYSLGTGGS 900 AVYRPQQPVA 910 PSASNTYPNT 920 PYISSASSYP 930 GQSQLYTAQH 940 QASPPTSSPT 950 ASFPLPPSSG 960 ASFQHGGPGA 970 PPSSSAYALP 980 PGTTESQSMP 990 DQASVLEGPQ 1000 NGWNDPPALN 1010 RVPKKKKMPE 1020 NFTPPVPITS 1030 PIMNPLGDPQ 1040 SQMLQQQPSA 1050 PVPLSSQASF 1060 LQPHLPGGQP 1070 FHGILQPLGQ 1080 VGMPPSFSKP 1090 NVEGAPGAPI 1100 GNTIQHVQSL 1110 PTEKITKKPI 1120 PDEHLVLKTT 1130 FEDLIQRCLS 1140 SATDPQTKRK 1150 LDDASKRLEF 1160 LYDKLREQTL 1170 SPTIISGLHN 1180 IARSIETRNY 1190 SKGLTIHTHV 1200 VSTSNFSETS 1210 AFMPVLKVVL TQAIKLGV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0012507 ER to Golgi transport vesicle membrane
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.