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Overview

Uniprot IDA0A5G2QUP2
Protein NameProtein transport protein Sec31A
Gene NameSEC31A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
111 SKIIAGDKEVVIAQN
1141 PTEKITKKPIPDEHL
1171 SATDPQTKRKLDDAS
1173 TDPQTKRKLDDASKR
206 RKNEPIIKVSDHSNR
441 VTEQEFLKRSDQLQQ
461 GFVSYCQKKIDASQT
462 FVSYCQKKIDASQTE
489 FEDDSRGKYLELLGY
621 TQKKYFAKSQSKITR
648 IVESCDLKNWREALA
71 SSSHRYHKLIWGPHK
803 PGHQESPKSPYERQQ

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Protein Sequence

10 MKLKEVDRTA 20 MQAWSPAQNH 30 PIYLATGTSA 40 QQLDATFSTS 50 ASLEIFELDL 60 SDPSLDMKSC 70 ATFSSSHRYH 80 KLIWGPHKMD 90 SQGNVSGVLI 100 AGGENGNTIL 110 YDPSKIIAGD 120 KEVVIAQNDK 130 HTGPVRALDV 140 NIFQTNLVAS 150 GANESEIYIW 160 DLNNFATPMT 170 PGAKTQPPED 180 ISCIAWNRQV 190 QHILASASPS 200 GRATVWDLRK 210 NEPIIKVSDH 220 SNRMHCSGLA 230 WHPDVATQMV 240 LASEDDRLPV 250 VQMWDLRFAS 260 SPLRVLENHA 270 RGILAIAWSM 280 ADPELLLTCG 290 KDAKILCSNP 300 NTGEVLYELP 310 TNTQWCFDIQ 320 WCPRNPAVLS 330 AASFDGRISV 340 YSIMGGSADG 350 LRQKQVDKLS 360 SSFGNLDPFG 370 TGQPLPPLQI 380 PQQTAQHSVV 390 LPLKKPPKWI 400 RRPVGASFSF 410 GGKLVTFASV 420 RAQPPQGAEP 430 QQPQQHHVLI 440 SQVVTEQEFL 450 KRSDQLQQVV 460 QSQGFVSYCQ 470 KKIDASQTEF 480 EKNVWSFLKV 490 NFEDDSRGKY 500 LELLGYRKED 510 LGKKIALALN 520 KVDGPDVALT 530 DSDQLAQSDG 540 EESPAAGEQL 550 LGERIKEEKQ 560 ESEFLPSAGG 570 TFNISVSGDI 580 DGLITQALLT 590 GDFESAVDLC 600 LHDNRMADAI 610 ILAIAGGQEL 620 LARTQKKYFA 630 KSQSKITRLI 640 TAVVMKDWKE 650 IVESCDLKNW 660 REALAAVLTY 670 AKPDEFSALC 680 DLLGTRLESE 690 GDSLLQTQAC 700 LCYICAGNVE 710 KLVACWTKAQ 720 DGSNPLSLQD 730 LIEKVVILRR 740 AVQLTQAVDT 750 NAVGVLLAEK 760 MSQYASLLAA 770 QGSIAAALAF 780 LPENTNQPNI 790 VQLRDRLCRA 800 QGDPAPGHQE 810 SPKSPYERQQ 820 LPKGRPGPVA 830 GHTQMPRVPA 840 QQYYPHVRIA 850 PTVTTWSNKT 860 PTALPSHPPA 870 ASPSDTQGEN 880 PPPPAFVMHG 890 SGHPNAGAPT 900 PLGHVHTQVP 910 PYPQPQPYQP 920 AQQYSLGTGG 930 SAVYRPQQPV 940 APSASNTYPN 950 TPYISSASSY 960 PGQSQLYTAQ 970 HQASPPTSSP 980 TASFPLPPSS 990 GASFQHGGPG 1000 APPSSSAYAL 1010 PPGTTGTLPA 1020 ASELPASQRT 1030 GPQNGWNDPP 1040 ALNRVPKKKK 1050 MPENFTPPVP 1060 ITSPIMNPLG 1070 DPQSQMLQQQ 1080 PSAPVPLSSQ 1090 ASFLQPHLPG 1100 GQPFHGILQP 1110 LGQVGMPPSF 1120 SKPNVEGAPG 1130 APIGNTIQHV 1140 QSLPTEKITK 1150 KPIPDEHLVL 1160 KTTFEDLIQR 1170 CLSSATDPQT 1180 KRKLDDASKR 1190 LEFLYDKLRE 1200 QTLSPTIISG 1210 LHNIARSIET 1220 RNYSKGLTIH 1230 THVVSTSNFS 1240 ETSAFMPVLK 1250 VVLTQAIKLG V

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030127 COPII vesicle coat
Cellular Component GO:0070971 endoplasmic reticulum exit site
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0048471 perinuclear region of cytoplasm
Molecular Function GO:0048306 calcium-dependent protein binding
Molecular Function GO:0005198 structural molecule activity
Biological Process GO:0090110 COPII-coated vesicle cargo loading
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0015031 protein transport
Biological Process GO:0051592 response to calcium ion

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.