Search Results
Overview
| Uniprot ID | A0A5G2QVD2 |
|---|---|
| Protein Name | NEDD8-activating enzyme E1 catalytic subunit |
| Gene Name | UBA3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 307 | RLTQGVVKRIIPAVA |
Function
Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8
Protein Sequence
10
MADGEEPEKK
20
RRRIEELLAE
30
KMAVDGGCGD
40
TGDWEGRWNH
50
VKKFLERSGP
60
FTHPDFEPST
70
ESLQFLLETC
80
KVLVIGAGGL
90
GCELLKNLAL
100
SGFRQIHVID
110
MDTIDVSNLN
120
RQFLFRPKDV
130
GRPKAEVAAE
140
FLNDRVPNCN
150
VVPHFNKIQD
160
FNDTFYRQFH
170
IIVCGLDSII
180
ARRWINGMLI
190
SLLNYEDGVL
200
DPSSIVPLID
210
GGTEGFKGNA
220
RVILPGMTAC
230
IECTLELYPP
240
QVNFPMCTIA
250
SMPRLPEHCI
260
EYVRILQWPK
270
EQPFGEGVPL
280
DGDDPDHIQW
290
IFQKSLERAS
300
QYNIRGVTYR
310
LTQGVVKRII
320
PAVASTNAVI
330
AAVCATEVFK
340
IATSAYIPLN
350
NYLVFNDVDG
360
LYTYTFEAER
370
KENCPACSQL
380
PQNIQFSPSA
390
KLQEVLDYLT
400
NSASLQMKSP
410
AITATLEGKN
420
RTLYLQSVTS
430
IEERTRPNLS
440
KTLKELGLVD
450
GQELAVADVT
460
TPQTVLFKLH
FTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0019781 | NEDD8 activating enzyme activity |
| Biological Process | GO:0045116 | protein neddylation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.