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Overview

Uniprot IDA0A5G2QVD9
Protein Name-
Gene NamePOGLUT3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
104 RTLSCPTKEPQIAKD
362 WKHYVPIKRNLSDLL

Function

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway

Protein Sequence

10 IVELLIIIFL 20 SGQTPFKVVI 30 KSLSPKEIVR 40 IHVPKPLDRN 50 DGTFLMRYRM 60 YETVNEGLKI 70 EVLYGDEHVA 80 QSPYILKGPV 90 YHEYCECPEE 100 DPQAWQRTLS 110 CPTKEPQIAK 120 DFASFPSINL 130 QQMLNEIPRR 140 FGEERGAIVH 150 YTILNNHIYR 160 RSLGKYTDFK 170 MFSDEILLSL 180 ARKVLLPDVE 190 FYVNLGDWPL 200 EHRKVNETPG 210 PLPIISWCGS 220 LDSRDVILPT 230 YDITHSTLEA 240 MRGVTNDLLS 250 IQGHTGPSWI 260 NKTEKAFFRG 270 RDSREERLQL 280 VQLSKENPQL 290 LDAGITGYFF 300 FQEKEKELGK 310 AKLIGFFDFF 320 KYKYQVNVDG 330 TVAAYRYPYL 340 MLGDSLVLKQ 350 DSPYYEHFYM 360 ALKPWKHYVP 370 IKRNLSDLLE 380 KIEWAKEHDE 390 EAKKIAKEGQ 400 LTARDLLQPH 410 RLYCYYYRVL 420 QKYAERQTSK 430 PEIRDGMELV 440 PQPDDSSSIC 450 QCHRKTPLRE EL

Gene Ontology

No Gene Ontology data available.

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.