Search Results
Overview
| Uniprot ID | A0A5G2QVG3 |
|---|---|
| Protein Name | NEDD8-activating enzyme E1 catalytic subunit |
| Gene Name | UBA3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 358 | RLTQGVVKRIIPAVA |
Function
Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8
Protein Sequence
10
MLTLLLFSLS
20
FREKKRRRIE
30
ELLAEKMAVD
40
GGCGDTGDWE
50
GRWNHVKKFL
60
ERSGPFTHPD
70
FEPSTESLQF
80
LLETCKVLVI
90
GAGGLGCELL
100
KNLALSGFRQ
110
IHVIDMDTID
120
VSNLNRQFLF
130
RPKDVGRPKA
140
EVAAEFLNDR
150
VPNCNVVPHF
160
NKIQDFNDTF
170
YRQFHIIVCG
180
LDSIIARRWI
190
NGMLISLLNY
200
EDGVLDPSSI
210
VPLIDGGTEG
220
FKGNARVILP
230
GMTACIECTL
240
ELYPPQVNFP
250
MCTIASMPRL
260
PEHCIEYVRI
270
LQWPKEQPFG
280
GNKPNFTIQI
290
YVRYLSMLFI
300
WKITLKISWS
310
LFTCFCLPFL
320
FFLPLTEGVP
330
LDGDDPDHIQ
340
WIFQKSLERA
350
SQYNIRGVTY
360
RLTQGVVKRI
370
IPAVASTNAV
380
IAAVCATEVF
390
KIATSAYIPL
400
NNYLVFNDVD
410
GLYTYTFEAE
420
RKENCPACSQ
430
LPQNIQFSPS
440
AKLQEVLDYL
450
TNSASLQMKS
460
PAITATLEGK
470
NRTLYLQSVT
480
SIEERTRPNL
490
SKTLKELGLV
500
DGQELAVADV
510
TTPQTVLFKL
HFTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0019781 | NEDD8 activating enzyme activity |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Biological Process | GO:0045116 | protein neddylation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.