Search Results
Overview
| Uniprot ID | A0A5G2QW85 |
|---|---|
| Protein Name | ER membrane protein complex subunit 2 |
| Gene Name | EMC2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 245 | ENLELSRKYFAQALK |
Function
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins
Protein Sequence
10
MRNGVEICHR
20
PVAGHVTSSP
30
RPLTPLPPGS
40
EKMAKVSELY
50
DVTWEEMRDK
60
MRKWREENSR
70
NSEQIVEVGE
80
ELINEYASKL
90
GDDIWIIYEQ
100
VMIAALDYGR
110
DDLALFCLQE
120
LRRQFPGSHR
130
VKRLTGMRFE
140
AMERYDDALQ
150
LYDRILQEDP
160
TNTAARKRKI
170
AIRKAQGKNV
180
EAIRELNEYL
190
EQFVGDQEAW
200
HELAELYINE
210
HDYAKAAFCL
220
EELMMTNPHN
230
HLYCQQYAEV
240
KYTQGGLENL
250
ELSRKYFAQA
260
LKLNNRNMRA
270
LFGLYMSASH
280
IASNPKASAK
290
TKKDNMKYAS
300
WAASQINRAY
310
QSSCHGSAET
320
NLRMRVQSLA
330
LLSELRILHC
340
CELWCRLQMQ
350
FDLVLLWLWY
RLAAAAQM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0072546 | EMC complex |
| Cellular Component | GO:0042406 | extrinsic component of endoplasmic reticulum membrane |
| Molecular Function | GO:0032977 | membrane insertase activity |
| Biological Process | GO:0045050 | protein insertion into ER membrane by stop-transfer membrane-anchor sequence |
| Biological Process | GO:0071816 | tail-anchored membrane protein insertion into ER membrane |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.