Search Results
Overview
| Uniprot ID | A0A5G2QXJ9 |
|---|---|
| Protein Name | Pachytene checkpoint protein 2 homolog |
| Gene Name | TRIP13 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 190 | TGKTSLCKALAQKLT |
| 195 | LCKALAQKLTIRLSS |
| 372 | LLSEISRKSEGLSGR |
Function
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways
Protein Sequence
10
MDEAVGDLKQ
20
ALPCVAEAPT
30
VHVEVHQRSG
40
STAKKEDVKL
50
NVRKLLNRHN
60
IVFGDYTWTE
70
FDEPFLTRNV
80
QSVSIVDTEL
90
KVKDPQPIDL
100
STCTVALHVF
110
QLNEGGPSSE
120
NLEEETENII
130
AANHWLLPAA
140
EFHGLWDSLV
150
YDAEVKSHLL
160
DYVMTTLLFS
170
DKNVDSNLIT
180
WNRVVLLHGP
190
PGTGKTSLCK
200
ALAQKLTIRL
210
SSRQGQWTQV
220
LKMFCFQSGK
230
LVTRMFQKIQ
240
DLIDDKDALV
250
FVLIDEVESL
260
TAARNACRAG
270
TEPSDAIRVV
280
NAVLTQIDQI
290
KRHSNVVILT
300
TSNITERIDV
310
AFVDRADIRQ
320
YVGPPSAAAI
330
FKIYLSCLEE
340
LMKCQIIYPR
350
QQLLTLRELE
360
MIGFIENNVS
370
KLSLLLSEIS
380
RKSEGLSGRV
390
LRKLPFLAHA
400
LYIQAPTVTI
410
EGFLQALSLA
420
VDRQFEDRKK
LSCV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0007131 | reciprocal meiotic recombination |
| Biological Process | GO:0007283 | spermatogenesis |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0048477 | oogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.