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Overview

Uniprot IDA0A5G2QY85
Protein NameProtein transport protein SEC23
Gene NameSEC23A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
193 SYVFRGTKDLSAKQL
312 RSWHDIEKDNAKYVK
323 KYVKKGTKHFEALAN
523 QLIRLCQKFGEYHKD
529 QKFGEYHKDDPSSFR

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Protein Sequence

10 MTTYLEFIQQ 20 NEERDGVRFS 30 WNVWPSSRLE 40 ATRMVVPVAA 50 LFTPLKERPD 60 LPPIQYEPVL 70 CSRTTCRAVL 80 NPLCQVDYRA 90 KLWACNFCYQ 100 RNQFPPTYAG 110 ISELNQPAEL 120 LPQFSSIEYV 130 VLRGPQMPLI 140 FLYVVDTCME 150 DEDLQALKES 160 MQMSLSLLPP 170 TALVGLITFG 180 RMVQVHELGC 190 EGISKSYVFR 200 GTKDLSAKQL 210 QEMLGLSKVP 220 VTQATRGPQV 230 QQFLQPVQKI 240 DMNLTDLLGE 250 LQRDPWPVPQ 260 GKRPLRSSGV 270 ALSIAVGLLE 280 CTFPNTGARI 290 MMFIGGPATQ 300 GPGMVVGDEL 310 KTPIRSWHDI 320 EKDNAKYVKK 330 GTKHFEALAN 340 RAATTGHVID 350 IYACALDQTG 360 LLEMKCCPNL 370 TGGYMVMGDS 380 FNTSLFKQTF 390 QRVFTKDMHG 400 QFKMGFGGTL 410 EIKEIGTGGT 420 CQWKICGLSP 430 TTTLAIYFEV 440 VNQHNAPIPQ 450 GGRGAIQFVT 460 QYQHSSGQRR 470 IRVTTIARNW 480 ADAQTQIQNI 490 AASFDQEAAA 500 ILMARLAIYR 510 AETEEGPDVL 520 RWLDRQLIRL 530 CQKFGEYHKD 540 DPSSFRFSET 550 FSLYPQFMFH 560 LRRSPFLQVF 570 NNSPDESSYY 580 RHHFMRQDLT 590 QSLIMIQPIL 600 YAYSFSGPPE 610 PVLLDSSSIL 620 ADRILLMDTF 630 FQILIYHGET 640 IAQWRKSGYQ 650 DMPEYENFRH 660 LLQAPVDDAQ 670 EILHSRFPMP 680 RYIDTEHGGS 690 QARFLLSKVN 700 PSQTHNNMYA 710 WGQESGAPIL 720 TDDVSLQVFM 730 DHLKKLAVSS AA

Gene Ontology

Classification GO ID Description
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0090114 COPII-coated vesicle budding
Biological Process GO:0006886 intracellular protein transport
Cellular Component GO:0030127 COPII vesicle coat
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005789 endoplasmic reticulum membrane

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.