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Overview

Uniprot IDA0A5G2QYC4
Protein NameGuanine nucleotide-binding protein G(s) subunit alpha
Gene NameGNAS
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
8 MGCLGNSKTEDQRNE

Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs)

Protein Sequence

10 MGCLGNSKTE 20 DQRNEEKAQR 30 EANKKIEKQL 40 QKDKQVYRAT 50 HRLLLLGAGE 60 SGKSTIVKQM 70 RILHVNGFNG 80 EGGEEDPQAA 90 RSNTSLPDGA 100 APPDALLRPF 110 QTIVAAMSNL 120 VPPVELANPE 130 NQFRVDYILS 140 VMNVPDFDFP 150 PEFYEHAKAL 160 WEDEGVRACY 170 ERSNEYQLID 180 CAQYFLDKID 190 VIKQADYVPS 200 DQDLLRCRVL 210 TSGIFETKFQ 220 VDKVNFHMFD 230 VGGQRDERRK 240 WIQCFNDVTA 250 IIFVVASSSY 260 NMVIREDNQT 270 NRLQEALNLF 280 KSIWNNRWLR 290 TISVILFLNK 300 QDLLAEKVLA 310 GKSKIEDYFP 320 EFARYTTPED 330 ATPEPGEDPR 340 VTRAKYFIRD 350 EFLRISTASG 360 DGRHYCYPHF 370 TCAVDTENIR 380 RVFNDCRDII 390 QRMHLRQYEL L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005834 heterotrimeric G-protein complex
Molecular Function GO:0031683 G-protein beta/gamma-subunit complex binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0007186 G protein-coupled receptor signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.