Search Results
Overview
| Uniprot ID | A0A5G2QYN9 |
|---|---|
| Protein Name | Histone acetyltransferase type B catalytic subunit |
| Gene Name | HAT1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 9 | EKFLVEYKSAVEKKL |
Function
Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac)
Protein Sequence
10
MEKFLVEYKS
20
AVEKKLAEYK
30
CNTNTAIELK
40
LVRFPEDLEN
50
DIRTFFPDIP
60
INSLGMSNET
70
AFGYKGLKIL
80
LYYIAGSLST
90
MFRVEYASKV
100
DENFDCVEAD
110
DVEGKIRQII
120
PPGFCTNTSD
130
FLSLLEKEVD
140
FKPFGTLLHT
150
YSVLSPTGGE
160
NFTFQIYKAD
170
MTCRGFREYH
180
ERLQTFLMWF
190
IETASFIDVD
200
DERWHYFLVF
210
EKYNKDGATL
220
FATVGYMTVY
230
NYYVYPDKTR
240
PRVSQMLILT
250
PFQGQGHGAQ
260
LLETVHRYYI
270
ASPSVLDITA
280
EDPSKSYVKL
290
RDFVLVKFCQ
300
GLPCFSREKL
310
MQGFNEDMAV
320
EAQQKFKINK
330
QHARRVYEIL
340
RLLVTDMSDA
350
EQYRSYRLDI
360
KRRLISPYKK
370
KQRDLAKMRK
380
CLRPEELTNQ
390
MNQIEISMQH
400
EQLEESFQEL
410
VEDYRRVIER
LAQE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000781 | chromosome, telomeric region |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004402 | histone acetyltransferase activity |
| Molecular Function | GO:0042393 | histone binding |
| Biological Process | GO:0031509 | subtelomeric heterochromatin formation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.