Search Results
Overview
| Uniprot ID | A0A5G2QZ15 |
|---|---|
| Protein Name | Gephyrin |
| Gene Name | GPHN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 138 | PVCGIRGKTLIINLP |
| 324 | TASCPTPKVQSRCSS |
Function
Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released
Protein Sequence
10
MATEGMILTN
20
HDHQIRVGVL
30
TVSDSCFRNL
40
AEDRSGINLK
50
DLVQDPSLLG
60
GTISAYKIVP
70
DEIEEIKETL
80
IDWCDEKELN
90
LILTTGGTGF
100
APRDVTPEAT
110
KEVIEREAPG
120
MALAMLMGSL
130
NVTPLGMLSR
140
PVCGIRGKTL
150
IINLPGSKKG
160
SQECFQFILP
170
ALPHAIDLLR
180
DAIVKVKEVH
190
DELEDLPSPP
200
PPLSPPPTTS
210
PHKQTEDKGV
220
QCEEEEEEKK
230
DSGVASTEDS
240
SSSHITAAAI
250
AAKKHPFYTS
260
PAVIMAHGEQ
270
PIPGLISYSH
280
DATGSAEEPI
290
PDSIISRGVQ
300
VLPRDTASLS
310
TTPSESPRAQ
320
ATSRLSTASC
330
PTPKVQSRCS
340
SKENILRASH
350
SAVDITKVAR
360
RHRMSPFPLT
370
SMDKAFITVL
380
EMTPVLGTEI
390
INYRDGMGRV
400
LAQDVYAKDN
410
LPPFPASVKD
420
GYAVRAADGP
430
GDRFIIGESQ
440
AGEQPTQTVM
450
PGQVMRVTTG
460
APIPCGADAV
470
VQVEDTELIR
480
ESDDGTEELE
490
VRILVQARPG
500
QDIRPIGHDI
510
KRGECVLAKG
520
THMGPSEIGL
530
LATVGVTEVE
540
VNKFPVVAVM
550
STGNELLNPE
560
DDLLPGKIRD
570
SNRSTLLATI
580
QEHGYPTINL
590
GIVGDNPDDL
600
LNALNEGISR
610
ADVIITSGGV
620
SMGEKDYLKQ
630
VLDIDLHAQI
640
HFGRVFMKPG
650
LPTTFATLDI
660
DGVRKIIFAL
670
PGNPVSAVVT
680
CNLFVVPALR
690
KMQGILDPRP
700
TIIKARLSCD
710
VKLDPRPEYH
720
RCILTWHHQE
730
PLPWAQSTGN
740
QMSSRLMSMR
750
SANGLLMLPP
760
KTEQYVELHK
770
GEVVDVMVIG
RL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0061598 | molybdopterin adenylyltransferase activity |
| Molecular Function | GO:0061599 | molybdopterin molybdotransferase activity |
| Biological Process | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process |
| Biological Process | GO:0072657 | protein localization to membrane |
| Biological Process | GO:0050808 | synapse organization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.