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Overview

Uniprot IDA0A5G2R0W2
Protein NameE3 ubiquitin-protein ligase RNF220
Gene NameRNF220
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
362 EYEWCGQKRIRATTL

Function

No function data available.

Protein Sequence

10 MDLHRAAFKM 20 ENSSYLPNPL 30 ASPALMVLAS 40 TAEASRDASI 50 PCQQPRPFGV 60 PVSVDKDVHI 70 PFTNGSYTFA 80 SMYHRQGGVP 90 GTFANRDFPP 100 SLLHLHPQFA 110 PPNLDCTPIS 120 MLNHSGVGAF 130 RPFASAEDRE 140 SYQSAFTPAK 150 RLKNCHDTES 160 PHLRFSDADG 170 KEYDFGTQLP 180 SSSPGSLKVD 190 DTGKKIFAVS 200 GLISDREASS 210 SPEDRNDRCK 220 KKAAALFDSQ 230 APICPICQVL 240 LRPSELQEHM 250 EQELEQLAQL 260 PSSKNSLLKD 270 AMAPGTPKSL 280 LLSASIKREG 290 ESPTASPHSS 300 ATDDLHHSDR 310 YQTFLRVRAN 320 RQTRLNARIG 330 KMKRRKQDEG 340 QREGSCMAEE 350 DAVDIEHENS 360 NRFEEYEWCG 370 QKRIRATTLL 380 EGGFRGSGFV 390 MCSGKENPDS 400 DADLDVDGDD 410 TLEYGKPQYT 420 EADVIPCTGE 430 EPGEAKEREA 440 LRGAVLNGGP 450 PSTRITPEFS 460 KWASDEMPST 470 SNGESSKQEA 480 MQKTCKNSDI 490 EKITEDSAVT 500 TFEALKARVR 510 ELERQLSRDR 520 YKCLICMDSY 530 SMPLTSIQCW 540 HVHCEECWLR 550 TLGAKKLCPQ 560 CNTITAPGDL RRIYL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005652 nuclear lamina
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0032991 protein-containing complex
Molecular Function GO:0008013 beta-catenin binding
Molecular Function GO:0061630 ubiquitin protein ligase activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway
Biological Process GO:0051865 protein autoubiquitination
Biological Process GO:0006513 protein monoubiquitination
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.