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Overview

Uniprot ID	A0A5G2R1C1
Protein Name	-
Gene Name	PTK7
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
1004	QPEGCPSKLYRLMQR
898	SNNRFVHKDLAARNC

Function

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis

Protein Sequence

10 MGAARGALSS 20 PRRLPLLSVL 30 LLPLLGGMQV 40 TCVRTVAATP 50 LTMLLPCSPS 60 AGAQAVIVFI 70 KEPSSQDALQ 80 GRRALLRCEV 90 EAPGPVHVYW 100 LLDGAPVEDT 110 ERRFAQGSSL 120 SFTAVDRLQD 130 SGAFQCVARD 140 DATGEEARSA 150 NASFNIKWIE 160 TGPVLLKHPA 170 SEAEIQPQTQ 180 VTLRCHIDGH 190 PRPTYQWFRD 200 GSPLADGQSN 210 HTVSSKERNL 220 TLRPASPEHS 230 GTYSCCAHNA 240 FGQACSSQNF 250 TLNIADESFA 260 RVMLAPQDVV 270 VARNEEAMFH 280 CQFSAQPPPS 290 LQWVFEDETP 300 ITNRSRPPHL 310 RRATVFANGS 320 LLLTQVRPRN 330 AGVYRCIGQG 340 QRGPPVVLEA 350 TLHLAEIEDM 360 APFEPRVFTA 370 GSEERVACTP 380 PQGLPAPLVW 390 WEHEGNRLPT 400 HGRVSQQGHE 410 LVFASTAESD 420 AGVYTCHAAN 430 LAGQRHQDVN 440 ITVATVPTWL 450 KKPQDSQLEE 460 GKPGYLHCLT 470 QATPKPTVVW 480 YRNQMLISED 490 SRFEVSKNGT 500 LRINSVEVYD 510 GTWYRCVSST 520 PAGSIEAQAR 530 VQVLEKLKFT 540 PPPRPQQCME 550 FDKEATVPCS 560 ATGREKPTIK 570 WVRADGSSLP 580 EWVTDNAGTL 590 HFSRVTRDDA 600 GNYTCIASNG 610 LQGQIRAHVQ 620 LTVAVFITFK 630 VEPERTTVYQ 640 GHTALLRCEA 650 QGDPKPLIQW 660 KDKPVPEESE 670 GPGSPPPYKM 680 IQTIGLSVGA 690 AVAYIIAVLG 700 LMFYCKKRCK 710 AKRLQKQPEG 720 EEPEMECLNG 730 GPLQNGQPSA 740 EIQEEVALTS 750 LGSGSAAANK 760 RHSTSDKMHF 770 PRASLQPITT 780 LGKSEFGEVF 790 LAKAQGLEEG 800 VAETLVLVKS 810 LQSRDEQQQL 820 DFRRELEMFG 830 KLSHPNVVRL 840 LGLCREAEPH 850 YMVLEYVDLG 860 DLKQFLRISK 870 SKDEKLKSQP 880 LSTKQKVALC 890 AQVALGMEHL 900 SNNRFVHKDL 910 AARNCLVSAQ 920 RQVKVSALGL 930 SKDVYNSEYY 940 HFRQAWVPLR 950 WMSPEAILEG 960 DFSTKSDVWA 970 FGVLMWEVFT 980 HGEMPHDGQA 990 DDEVLADLQA 1000 GKARLPQPEG 1010 CPSKLYRLMQ 1020 RCWALSPKDR 1030 PSFSEIANAL GDSSADSKP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0070161	anchoring junction
Cellular Component	GO:0016020	membrane
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0046872	metal ion binding
Molecular Function	GO:0004672	protein kinase activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.