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Overview

Uniprot IDA0A5G2R297
Protein NameDual specificity mitogen-activated protein kinase kinase 1
Gene NameMAP2K1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
90 KLIHLEIKPAIRNQI

Function

No function data available.

Protein Sequence

10 MCVRGELCRM 20 GPPTNLEALQ 30 KKLEELELDE 40 QQRKRLEAFL 50 TQKQKVGELK 60 DDDFEKISEL 70 GAGNGGVVFK 80 VSHKPSGLVM 90 ARKLIHLEIK 100 PAIRNQIIRE 110 LQVLHECNSP 120 YIVGFYGAFY 130 SDGEISICME 140 HMDGGSLDQV 150 LKKAGRIPEQ 160 ILGKVSIAVI 170 KGLTYLREKH 180 KIMHRDVKPS 190 NILVNSRGEI 200 KLCDFGVSGQ 210 LIDSMANSFV 220 GTRSYMSPER 230 LQGTHYSVQS 240 DIWSMGLSLV 250 EMAVGRYPIP 260 PPDAKELELM 270 FGCQVEGDAA 280 ETPPRPRTPG 290 RPLSSYGMDS 300 RPPMAIFELL 310 DYIVNEPPPK 320 LPSGVFSLEF 330 QDFVNKCFSP 340 FSHIQVHAFI 350 KRSDAEEVDF 360 AGWLCSTIGL 370 NQPSTPTHAA GV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005769 early endosome
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0005770 late endosome
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005634 nucleus
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004708 MAP kinase kinase activity
Molecular Function GO:0004674 protein serine/threonine kinase activity
Molecular Function GO:0004713 protein tyrosine kinase activity
Biological Process GO:2000641 regulation of early endosome to late endosome transport
Biological Process GO:0090170 regulation of Golgi inheritance
Biological Process GO:0032872 regulation of stress-activated MAPK cascade

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.