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Overview

Uniprot IDA0A5G2R3W8
Protein NameKinesin-like protein
Gene NameKIF23
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
183 REATPNPKTPSSKRQ
588 ETTMKWEKECERRVA
608 MQNKLWVKDEKLKQL
727 EIETKLIKGDVYKTR
732 LIKGDVYKTRGGGQS

Function

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro

Protein Sequence

10 MKPARTKTPR 20 KPPVKKGAQT 30 TLKDPVGVYC 40 RVRPLSLLDQ 50 ECCIEVINNT 60 TVQLHTPEGY 70 RLNRNGDYKE 80 TQYSFKQVFG 90 THTTQKELFD 100 VVANPLVDDL 110 IHGKNGLLFT 120 YGVTGSGKTH 130 TMTGSPGEGG 140 LLPRCLDMIF 150 NSIGSFQAKR 160 YVFKSNDRNS 170 MDIQCEVDAL 180 LERQKREATP 190 NPKTPSSKRQ 200 VDPEFVDMIN 210 VQEFCKAEEV 220 DEDSVYGVFV 230 SYIEIYNNYI 240 YDLLEEVPFD 250 PIKPKPPQSK 260 LLREDKNHNM 270 YVAGCTEVEV 280 KSTEEAFEVF 290 WRGQKKRRIA 300 NTHLNRESSR 310 SHSVFNIKLV 320 QAPLDADGDN 330 VLQEKEQITI 340 SQLSLVDLAG 350 SERTNRTKAE 360 GNRLREAGNI 370 NQSLMTLRTC 380 MEVLRENQMY 390 GTNKQVMRFA 400 EVTQEVEVAR 410 PIDRPICGLT 420 PGRRYRNQAR 430 GGPVGDEPLV 440 SEMVLQSFPP 450 LPPCEILNIN 460 DEQTLPRLIE 470 ALEKRHQLRQ 480 MMTDEFNKQA 490 ITFKALLQEF 500 DNAVLNKENY 510 IQGKLNEKEK 520 VISGQKLEIE 530 RLEKKNKTLE 540 YKIEILEKTT 550 TIYEEDKRSL 560 QQELETQNQK 570 LQRQFSDKRR 580 LEARLQGMMT 590 ETTMKWEKEC 600 ERRVAAKQLE 610 MQNKLWVKDE 620 KLKQLKAIVT 630 EPRTEKPERP 640 SRERDREKVT 650 QRSVSPPPVP 660 NAPPIRLRHR 670 RSRSAGDRWV 680 DHKPASNVQT 690 ETVMQPHVPH 700 AITVSVANEK 710 ALAKCEKYML 720 THQELASDGE 730 IETKLIKGDV 740 YKTRGGGQSV 750 QFTDIETLKQ 760 ESPTGRKRRS 770 STAAPAQPDG 780 TESEWTDVET 790 RCSVAVEMRA 800 GSQLGPGYQH HAQPKRKKP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0005874 microtubule
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005819 spindle
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008017 microtubule binding
Molecular Function GO:0003777 microtubule motor activity
Biological Process GO:0051301 cell division
Biological Process GO:0007018 microtubule-based movement

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.