Search Results
Overview
| Uniprot ID | A0A5G2R457 |
|---|---|
| Protein Name | Calcyclin-binding protein |
| Gene Name | CACYBP |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 141 | ISVEGSSKKVKTDTV |
| 169 | DYLTQVEKECKEKEK |
| 17 | EVKVLLEKATRKRVR |
| 210 | DMKRTINKAWVESRE |
| 83 | YGWDQSDKFVKIYIT |
Function
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1)
Protein Sequence
10
LGSLQKDLEE
20
VKVLLEKATR
30
KRVRDTLTTE
40
KSKIETEIKN
50
KMQQKSQRKA
60
ELLENEKPAA
70
VVAPITTGYT
80
VKISNYGWDQ
90
SDKFVKIYIT
100
LTGVHQVPTE
110
NVQVHFTERS
120
FDLLVKNLNG
130
KNYSMIVNNL
140
LKPISVEGSS
150
KKVKTDTVLI
160
LCRKKAENTR
170
WDYLTQVEKE
180
CKEKEKPSYD
190
TETDPSEGLM
200
NVLKKIYEDG
210
DDDMKRTINK
220
AWVESREKQA
KGDTEF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0044548 | S100 protein binding |
| Molecular Function | GO:0015631 | tubulin binding |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.