Search Results
Overview
| Uniprot ID | A0A5G2R496 |
|---|---|
| Protein Name | DNA-directed RNA polymerases I and III subunit RPAC1 |
| Gene Name | POLR1C |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 159 | TRNPSAAKDSSDPNE |
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft
Protein Sequence
10
MVELKMAAAQ
20
AVEEMRSRVV
30
LGEFGVRNVH
40
TTDFPGNYSG
50
YDDAWDQDRF
60
EKNFRVDVVH
70
MDENSLEFDM
80
VGIDAAIANA
90
FRRILLAEVP
100
TMAVEKVLVY
110
NNTSIVQDEI
120
LAHRLGLIPI
130
HADPRLFEYR
140
NLGDEEGTEI
150
DTLQFRLQVR
160
CTRNPSAAKD
170
SSDPNELYVN
180
HKVYTRHMTW
190
VPLGNQADLF
200
PEGTIRPVHD
210
DILIAQLRPG
220
QEIDLLMQCV
230
KGIGKDHAKF
240
SPVATASYRL
250
LPDITLLEPV
260
EGDAAEELSR
270
CFSPGVIEVQ
280
EIQGKKVARV
290
ANPRLDTFSR
300
EVFRNDMLKK
310
VVRLARVRDH
320
YIFSVESTGV
330
LPPDVLVSEA
340
IKVLMGKCRR
350
FLDELDAVQM
D
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005736 | RNA polymerase I complex |
| Cellular Component | GO:0005666 | RNA polymerase III complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003899 | DNA-directed RNA polymerase activity |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Biological Process | GO:0006386 | termination of RNA polymerase III transcription |
| Biological Process | GO:0006362 | transcription elongation by RNA polymerase I |
| Biological Process | GO:0006384 | transcription initiation at RNA polymerase III promoter |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.