Search Results
Overview
| Uniprot ID | A0A5G2R4Z0 |
|---|---|
| Protein Name | ADP-ribosylation factor-like protein 1 |
| Gene Name | ARL1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 118 | LEEEELRKAILVVFA |
| 157 | DRKWQIFKTSATKGT |
Function
GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells
Protein Sequence
10
MGGFFSSIFS
20
SLFGTREMRI
30
LILGLDGAGK
40
TTILYRLQVG
50
EVVTTIPTIG
60
FNVETVTYKN
70
LKFQVWDLGG
80
QTSIRPYWRC
90
YYSNTDAVIY
100
VVDSCDRDRI
110
GISKSELVAM
120
LEEEELRKAI
130
LVVFANKQDM
140
EQAMTPSEMA
150
NSLGLPALKD
160
RKWQIFKTSA
170
TKGTGLDEAM
180
EWLSIMFLEV
190
ICVFVCTCSC
200
VQMCNFPLVL
MKFRLLS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005802 | trans-Golgi network |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:1990583 | phospholipase D activator activity |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Biological Process | GO:0034067 | protein localization to Golgi apparatus |
| Biological Process | GO:0042147 | retrograde transport, endosome to Golgi |
| Biological Process | GO:0009404 | toxin metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.