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Overview

Uniprot IDA0A5G2R585
Protein NameTapasin
Gene NameTAPBP
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
42 GRGQLSKKPAALLLR

Function

Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)

Protein Sequence

10 MKPLSLLLSV 20 VALGLASTVS 30 AGPAVIECWF 40 VEDAGRGQLS 50 KKPAALLLRQ 60 GPGSPPPRPD 70 LEPELYLKVH 80 AVLTVITHTP 90 APRIRLGQDA 100 LLDLSFAYVP 110 PTSKAAISLA 120 PGPPPFGLEW 130 RRQHLGKGHL 140 LLAATPGLSG 150 QVPAAREGAV 160 AFAAWDDDEP 170 WGPWTGNGSF 180 WLPAVQPFQE 190 GTYLATVHLP 200 YLQGQVAMDL 210 AVQKSPKVSL 220 TPAPLVWAAP 230 GEAPPELLCL 240 VSHFYPSEGL 250 EVEWELRGGP 260 QGRFQKAEGQ 270 SWHSALSHHA 280 DGSVSLSAHL 290 QLPPVTTEQH 300 GARYACRVHH 310 PSLPALGRRS 320 EITLQVAGLS 330 GPSLEDGVGL 340 FLSAFLLLGL 350 IKALGWAAAH 360 LAASRDSTQK 370 VTVLLPHLSL 380 LVVSPPPTPH 390 SRARPQAWWA 400 SQGLGIHTDL 410 SNPATKNILH LLPWV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0030670 phagocytic vesicle membrane
Molecular Function GO:0042605 peptide antigen binding
Biological Process GO:0002474 antigen processing and presentation of peptide antigen via MHC class I

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.