Search Results

Overview

Uniprot IDA0A5G2R593
Protein NameEukaryotic translation initiation factor 4 gamma 2
Gene NameEIF4G2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
187 RNVDVYDKRENPLLP
206 QRAIAKIKMLGNIKF
233 SILHKCIKTLLEKKK
271 RLDHERAKSLMDQYF
31 GAPQHYPKTAGNSEF
313 EHHWVPRKAFLDNGP
321 AFLDNGPKTINQIRQ
41 GNSEFLGKTPGQNAQ
529 NPPLIQEKPAKTSKK
739 KLEKELLKQIKLDPS
755 QTIYKWIKDNISPKL
87 KVRGILNKLTPEKFD
880 ITQEFPGKGKALFQV

Function

Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases

Protein Sequence

10 VESAIAEGGA 20 SRFSASSGGG 30 GSRGAPQHYP 40 KTAGNSEFLG 50 KTPGQNAQKW 60 IPARSTRRDD 70 NSAANNSANE 80 KERHDAIFRK 90 VRGILNKLTP 100 EKFDKLCLEL 110 LNVGVESKLI 120 LKGVILLIVD 130 KALEEPKYSS 140 LYAQLCLRLA 150 EDAPNFDGPA 160 AEGQPGQKQS 170 TTFRRLLISK 180 LQDEFENRTR 190 NVDVYDKREN 200 PLLPEEEEQR 210 AIAKIKMLGN 220 IKFIGELGKL 230 DLIHESILHK 240 CIKTLLEKKK 250 RVQLKDMGED 260 LECLCQIMRT 270 VGPRLDHERA 280 KSLMDQYFAR 290 MCSLMLSKEL 300 PARIRFLLQD 310 TVELREHHWV 320 PRKAFLDNGP 330 KTINQIRQDA 340 VKDLGVFIPA 350 PMAQGMRSDF 360 FLEGPFMPPR 370 MKMDRDPLGG 380 LADMFGQMPG 390 SGIGTGPGVI 400 QDRFSPTMGR 410 HRSNQLFNGH 420 GGHIMPPTQS 430 QFGEMGGKFM 440 KSQGLSQLYH 450 NQSQGLLSQL 460 QGQSKDMPPR 470 FSKKGQLNAD 480 EISLRPAQSF 490 LMNKNQVPKL 500 QPQITMIPPS 510 AQPPRTQTPP 520 LGQTPQLGLK 530 TNPPLIQEKP 540 AKTSKKPPPS 550 KEELLKLTET 560 VVTEYLNSGN 570 ANEAVNGVRE 580 MRAPKHFLPE 590 MLSKVIILSL 600 DRSDEDKEKA 610 SSLISLLKQE 620 GIATSDNFMQ 630 AFLNVLDQCP 640 KLEVDIPLVK 650 SYLAQFAARA 660 IISELVSISE 670 LAQPLESGTH 680 FPLFLLCLQQ 690 LAKLQDREWL 700 TELFQQSKVN 710 MQKMLPEIDQ 720 NKDRMLEILE 730 GKGLSFLFPL 740 LKLEKELLKQ 750 IKLDPSPQTI 760 YKWIKDNISP 770 KLHVDKGFVN 780 ILMTSFLQYI 790 SSEVNPPSDE 800 TDSSSAPSKE 810 QLEQEKQLLL 820 SFKPVMQKFL 830 HDHVDLQVSA 840 LYALQVHCYN 850 SNFPKGMLLR 860 FFVHFYDMEI 870 IEEEAFLAWK 880 EDITQEFPGK 890 GKALFQVNQW 900 LTWLETAEEE ESEEEAD

Gene Ontology

Classification GO ID Description
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003743 translation initiation factor activity
Biological Process GO:0006446 regulation of translational initiation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.