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Overview

Uniprot ID	A0A5G2R5N9
Protein Name	Serotransferrin
Gene Name	TF
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
554	AFRCLVEKGDVAFVK

Function

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation

Protein Sequence

10 MRLAVRALLA 20 CAVLGLSLAV 30 AQKTVRWCTI 40 SNQEANKCSS 50 FRENMSKAVK 60 NGPLVSCVKK 70 SSYLDCIKAI 80 RDKEADAVTL 90 DAGLVFEAGL 100 APYNLKPVVA 110 EFYGQKDNPQ 120 THYYAVAVVK 130 KGSNFQWNQL 140 QGKRSCHTGL 150 GRSAGWIIPM 160 GLLYDQLPEP 170 RKPIEKAVAS 180 FFSSSCVPCA 190 DPVNFPKLCQ 200 QCAGKGAEKC 210 ACSNHEPYFG 220 YAGAFNCLKE 230 DAGDVAFVKH 240 STVLENLPDK 250 ADRDQYELLC 260 RDNTRRPVDD 270 YENCYLAQVP 280 SHAVVARSVD 290 GQEDSIWELL 300 NQAQEHFGRD 310 KSPDFQLFSS 320 SHGKDLLFKD 330 SANGFLRPSK 340 MDSSLYLGYQ 350 YVTALRNLRE 360 EISPDSSKNE 370 CKKVRWCAIG 380 HEETQKCDAW 390 SINSGGKIEC 400 VSAENTEDCI 410 AKIVKGEADA 420 MSLDGGYIYI 430 AGKCGLVPVL 440 AENYKTEGEN 450 CVNTPEKGYL 460 AVAVVKKSSG 470 PDLNWNNLKG 480 KKSCHTAVDR 490 TAGWNIPMGL 500 LYNKINSCKF 510 DQFFGEGCAP 520 GSQRNSSLCA 530 LCIGSERAPG 540 RECLANNHER 550 YYGYTGAFRC 560 LVEKGDVAFV 570 KDQVVQQNTD 580 GKNKDDWAKD 590 LKQMDFELLC 600 QNGAREPVDN 610 AENCHLARAP 620 NHAVVARDDK 630 VTCVAEELLK 640 QQAQFGRHVT 650 DCSSSFCMFK 660 SNTKDLLFRD 670 DTQCLARVGK 680 TTYESYLGAD 690 YITAVANLRK 700 CSTSKLLEAC 710 TFHSAKNPRV ETTT

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005615	extracellular space
Molecular Function	GO:0008199	ferric iron binding
Biological Process	GO:0006879	intracellular iron ion homeostasis
Biological Process	GO:0006826	iron ion transport
Biological Process	GO:0051241	negative regulation of multicellular organismal process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.