Search Results

Overview

Uniprot IDA0A5G2R5T4
Protein NameDNA repair protein Ku70
Gene NameXRCC6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
294 RETNEPVKTKTRTFN
328 NRQIVLEKEETEMLK
536 PDYNPEGKAPKRKQD
553 SCGSKRPKVELSEEE
572 ISEGTLGKLTVPTLK

Function

No function data available.

Protein Sequence

10 MSGWESYYKN 20 QGDEEEEEEG 30 RETGEDYRCS 40 GRDSLIFLVD 50 ASRAMFESQD 60 EDELTPFDMS 70 IQCIQSVYTN 80 KIISSDRDLL 90 AVVFYGTKKD 100 KNSVNFKNIY 110 VLQELDSPGA 120 KRVQELDRFK 130 GQEGTKYFQD 140 LLGHGSDYSL 150 SEVLWVCANL 160 FSDVQVKMSH 170 KRIMLFTNDD 180 DPHGNDSAKA 190 SRARTKAGDL 200 RDTGIFLDLM 210 HLKKPGGFDI 220 SLFYRDIISV 230 AEDEDIGVHF 240 EESHKLEDLL 250 RKVRAKETRK 260 RVLHRLKLKL 270 SKDVALTVGI 280 YNLVQKAYKP 290 FPVRLCRETN 300 EPVKTKTRTF 310 NVNTGSLLLP 320 SDTKRSQTYG 330 NRQIVLEKEE 340 TEMLKRFDEP 350 GLILIGFKPL 360 GMLKRHHYVR 370 PSLFVYPEES 380 LVNGSSTLFT 390 ALLTKCLEKE 400 VMAVCRYTPR 410 KNLPPYFVAL 420 MPQEEELDDQ 430 KVQVTPPGFQ 440 LVFLPYADDK 450 RKVPFTEKIM 460 ANPEQVDKMK 470 AIVQKLRFKY 480 RSDSFENPVL 490 QQHFRNMEAL 500 ALDLMEPEQA 510 VDLTLPKAEA 520 MAKRLGSLVD 530 EFKELVYPPD 540 YNPEGKAPKR 550 KQDNESCGSK 560 RPKVELSEEE 570 LKAHISEGTL 580 GKLTVPTLKE 590 ACRVHGVKGG 600 MKKQELLDAL TKHFQD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005694 chromosome
Molecular Function GO:0042162 telomeric DNA binding
Molecular Function GO:0000976 transcription cis-regulatory region binding
Biological Process GO:0002218 activation of innate immune response
Biological Process GO:0071480 cellular response to gamma radiation
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0097680 double-strand break repair via classical nonhomologous end joining
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0045087 innate immune response
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0048660 regulation of smooth muscle cell proliferation
Biological Process GO:0000723 telomere maintenance
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex
Cellular Component GO:0043564 Ku70:Ku80 complex
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0032993 protein-DNA complex
Cellular Component GO:0005667 transcription regulator complex
Molecular Function GO:0051575 5'-deoxyribose-5-phosphate lyase activity
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0030332 cyclin binding
Molecular Function GO:0003684 damaged DNA binding
Molecular Function GO:0045027 DNA end binding
Molecular Function GO:0003678 DNA helicase activity
Molecular Function GO:0003691 double-stranded telomeric DNA binding
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0097110 scaffold protein binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.