Search Results

Overview

Uniprot IDA0A5G2R693
Protein NameTubulin beta chain
Gene NameTUBB3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
58 YNEASSHKYVPRAIL

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 MREIVHIQAG 20 QCGNQIGAKF 30 WEVISDEHGI 40 DPSGNYVGDS 50 DLQLERISVY 60 YNEASSHKYV 70 PRAILVDLEP 80 GTMDSVRSGA 90 FGHLFRPDNF 100 IFGQSGAGNN 110 WAKGHYTEGA 120 ELVDSVLDVV 130 RKECENCDCL 140 QGFQLTHSLG 150 GGTGSGMGTL 160 LISKVREEYP 170 DRIMNTFSVV 180 PSPKVSDTVV 190 EPYNATLSIH 200 QLVENTDETY 210 CIDNEALYDI 220 CFRTLKLATP 230 TYGDLNHLVS 240 ATMSGVTTSL 250 RFPGQLNADL 260 RKLAVNMVPF 270 PRLHFFMPGF 280 APLTARGSQQ 290 YRALTVPELT 300 QQMFDAKNMM 310 AACDPRHGRY 320 LTVATVFRGR 330 MSMKEVDEQM 340 LAIQSKNSSY 350 FVEWIPNNVK 360 VAVCDIPPRG 370 LPALQHERPG 380 VRVPAVPGRH 390 GRRGGRDVRG 400 RRGGVRGPGP 410 QVRRPGGGRG 420 TARTQRSAPS 430 RVAPDTARPR 440 PTRPERVAPG 450 PPSVRPAVFA 460 ASLPRPSPPS 470 HPPPSVISVV 480 CGPLCLLYCP LQA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071944 cell periphery
Cellular Component GO:0097542 ciliary tip
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030425 dendrite
Cellular Component GO:0030175 filopodium
Cellular Component GO:0030426 growth cone
Cellular Component GO:0045171 intercellular bridge
Cellular Component GO:0030027 lamellipodium
Cellular Component GO:0005874 microtubule
Cellular Component GO:0072686 mitotic spindle
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0097229 sperm end piece
Cellular Component GO:0097228 sperm principal piece
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:1990890 netrin receptor binding
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0007411 axon guidance
Biological Process GO:1990791 dorsal root ganglion development
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0000278 mitotic cell cycle

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.