Search Results
Overview
| Uniprot ID | A0A5G2R6D0 |
|---|---|
| Protein Name | Serine hydroxymethyltransferase |
| Gene Name | SHMT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 259 | VVTTTTHKTLRGARS |
| 334 | EYSLQVLKNARAMAD |
| 442 | EVKSKTTKLQDFKSF |
| 447 | TTKLQDFKSFLLKDP |
| 452 | DFKSFLLKDPETCRR |
| 82 | YSEGYPGKRYYGGAE |
Function
Interconversion of serine and glycine
Protein Sequence
10
MAIRSQHSEA
20
AQTQTGEATK
30
GWSGQESLSD
40
SDPEMWELLR
50
REKDRQCRGL
60
ELIASENFCS
70
RAALEALGSC
80
LNNKYSEGYP
90
GKRYYGGAEV
100
VDEIELLCQR
110
RALEAFDLDP
120
AQWGVNVQPY
130
SGSPANLAAY
140
TALLQPHDRI
150
MGLDLPDGGH
160
LTHGYMTDVK
170
RISATSIFFE
180
SMPYKLNPKT
190
GLIDYDQLAL
200
TARLFRPRLI
210
IAGTSAYARL
220
IDYARMREVC
230
DEVKAHLLAD
240
MAHISGLVAA
250
KVIPSPFEHA
260
DVVTTTTHKT
270
LRGARSGLIF
280
YRKGVRTVDP
290
KTGREIPYTF
300
EDRINFAVFP
310
SLGGPHNHAI
320
AAVAVALKQA
330
CTPMFREYSL
340
QVLKNARAMA
350
DALLERGYSL
360
VSGGTDNHLV
370
LVDLRPKGLD
380
GARVERVLEL
390
VSITANKNTC
400
PGDRSAITPG
410
GLRLGTPALT
420
SRQFREDDFR
430
KVVAFIDEGV
440
SIGLEVKSKT
450
TKLQDFKSFL
460
LKDPETCRRL
470
ADLRQRVEQF
480
ARAFPMPGFE
EH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0070013 | intracellular organelle lumen |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004372 | glycine hydroxymethyltransferase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
| Biological Process | GO:0019264 | glycine biosynthetic process from L-serine |
| Biological Process | GO:0051289 | protein homotetramerization |
| Biological Process | GO:0006417 | regulation of translation |
| Biological Process | GO:0035999 | tetrahydrofolate interconversion |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.