Search Results
Overview
| Uniprot ID | A0A5G2R7J0 |
|---|---|
| Protein Name | Drebrin |
| Gene Name | DBN1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 273 | EEETQMKKSESEVEE |
| 297 | DNPREFFKQQERVAS |
Function
Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines. Involved in memory-related synaptic plasticity in the hippocampus
Protein Sequence
10
MARRPCHATA
20
ALAGGQARRD
30
GLERQALVSC
40
GALYTYEDGS
50
DDLKLAASGD
60
GGLQELSGHF
70
ENQKVMYGFC
80
SVKDSQAALP
90
KYVLINWVGE
100
DVPDARKCAC
110
ASHVAKVAEF
120
FQGVDVIVNA
130
SSVEDIDAGA
140
IGQRLSNGLA
150
RLSSPVLHRL
160
RLREDENAEP
170
VGTTYQKTDA
180
AVEMKRINRE
190
QFWEQAKKEE
200
ELRKEEERKK
210
ALDERLRFEQ
220
ERMEQERQEQ
230
EERERRYRER
240
EQQIEEHRRK
250
QQTLEAEEAK
260
RRLQEQSIFG
270
DQRDEEEETQ
280
MKKSESEVEE
290
AAAIIAQRPD
300
NPREFFKQQE
310
RVASASAGSC
320
DVPSPFNHRP
330
GSHLDSHRRM
340
APTPIPARSP
350
SDSSTASTPV
360
AEQIERALDE
370
VTSSQPPPLP
380
PPPPPAQETQ
390
EPSPGLDSEE
400
TSKEAREAAP
410
QAWAGPVEEP
420
PQAPEPPQGR
430
GSPPEDLMFM
440
ASTEQAVLAA
450
PLEPAMAGAS
460
AADTLVADAI
470
EADTAAADTA
480
VANTVTPAAA
490
SLIDLWPGNG
500
EEASAPQAEP
510
RAPTPPSGAE
520
VPLAEVPLLD
530
EVAQEPLPPA
540
GEGSANLLNF
550
DELPEPPATF
560
CDQEEEVEGV
570
SLAVPQAPTL
580
PSALEELDLE
590
PEPEPHLLTN
600
GETTQKEGTQ
610
ASEGYFSQSQ
620
EEEFAQSEEL
630
CAKAPPPVFY
640
NKPPEIDITC
650
WDADPVPEEE
EGFEGGD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070161 | anchoring junction |
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0030426 | growth cone |
| Molecular Function | GO:0003779 | actin binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.