Search Results

Overview

Uniprot IDA0A5G2R7K7
Protein NameIntegrin beta
Gene NameITGB3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
427 AYGKIRSKVELEVRD
485 GCPREKEKSFTIKPV
490 KEKSFTIKPVGFKDS
691 KKGCVECKKFNRGSL
716 RDEIESVKELQDSGK

Function

No function data available.

Protein Sequence

10 MNFSHLLPSP 20 CPLPNSLCLV 30 NVYGMVKVCL 40 CPKCLWDGKV 50 CKPGHLGSIG 60 EGWGRPVTSS 70 SHITCKCLCL 80 SVAGPNICAT 90 RGVSSCQQCL 100 AVSPMCAWCS 110 DEDLPLGTPR 120 CNLEENLLND 130 HCNPKYIEFP 140 ISEARILEAR 150 PLSDKGSGDS 160 SQITQVSPQR 170 ILLRLRPDDS 180 KSFSVQVRQV 190 EDYPVDIYYL 200 MDLSFSMKDD 210 LESIQNLGTK 220 LASQMRKLTS 230 NLRIGFGAFV 240 DKPVSPYMYI 250 SPPQALKNPC 260 YDMKTTCLPM 270 FGYKHVLTLT 280 DQVTRFNEEV 290 KKQNVSRNRD 300 APEGGFDAIM 310 QATVCDEKIG 320 WRNDASHLLV 330 FTTDAKTHIA 340 LDGRLAGIVQ 350 PNDGQCHVGS 360 DNHYSASTTM 370 DYPSLGLITE 380 KLSQKNINLI 390 FAVTEGVVSL 400 YQNYSELIPG 410 TTVGVLSSNS 420 SNVLQLIVDA 430 YGKIRSKVEL 440 EVRDLPEELS 450 LSFNATCLNN 460 EVIPGLKSCV 470 GLKIGDTVSF 480 SIEAKVRGCP 490 REKEKSFTIK 500 PVGFKDSLTV 510 QVTFNCDCDC 520 QAQAEPDSPR 530 CNNGNGTFEC 540 GVCHCGPGWL 550 GFQCECSEKD 560 YRPSQQDECS 570 PQQGQPICSQ 580 RGECLCGQCV 590 CHSSDFGKIT 600 GKYCECDDFS 610 CVHYKGEMCS 620 GHGQCSCGDC 630 LCDSDWTGFY 640 CNCTTRTDTC 650 LSSNGLLCSG 660 RGNCECGSCV 670 CIQPGSYGDT 680 CEKCPTCPDA 690 CTFKKGCVEC 700 KKFNRGSLYE 710 ANTCNRYCRD 720 EIESVKELQD 730 SGKNAVNCTY 740 KNEDDCVVRF 750 QYYEDSSGKS 760 ILYVVEEPEC 770 PKGPDILVVL 780 LSVMGAILLI 790 GLATLLIWKL 800 LITIHDRKEF 810 AKFEEERARA 820 KWDTANNPLY 830 KEATSTFTNI TYRGT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071133 alpha9-beta1 integrin-ADAM8 complex
Cellular Component GO:0035868 alphav-beta3 integrin-HMGB1 complex
Cellular Component GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
Cellular Component GO:0035866 alphav-beta3 integrin-PKCalpha complex
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0005911 cell-cell junction
Cellular Component GO:0009897 external side of plasma membrane
Cellular Component GO:0031527 filopodium membrane
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0070442 integrin alphaIIb-beta3 complex
Cellular Component GO:0034683 integrin alphav-beta3 complex
Cellular Component GO:0031258 lamellipodium membrane
Cellular Component GO:0042470 melanosome
Cellular Component GO:0031528 microvillus membrane
Cellular Component GO:0005634 nucleus
Cellular Component GO:0045211 postsynaptic membrane
Cellular Component GO:0032587 ruffle membrane
Molecular Function GO:0019960 C-X3-C chemokine binding
Molecular Function GO:0004895 cell adhesion receptor activity
Molecular Function GO:0050840 extracellular matrix binding
Molecular Function GO:0017134 fibroblast growth factor binding
Molecular Function GO:0001968 fibronectin binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0031994 insulin-like growth factor I binding
Molecular Function GO:0005178 integrin binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0038132 neuregulin binding
Molecular Function GO:0002020 protease binding
Molecular Function GO:0003756 protein disulfide isomerase activity
Molecular Function GO:0005080 protein kinase C binding
Molecular Function GO:0043184 vascular endothelial growth factor receptor 2 binding
Biological Process GO:0038027 apolipoprotein A-I-mediated signaling pathway
Biological Process GO:0043277 apoptotic cell clearance
Biological Process GO:0033631 cell-cell adhesion mediated by integrin
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0048333 mesodermal cell differentiation
Biological Process GO:0050919 negative chemotaxis
Biological Process GO:0010888 negative regulation of lipid storage
Biological Process GO:0032369 negative regulation of lipid transport
Biological Process GO:0050748 negative regulation of lipoprotein metabolic process
Biological Process GO:0010745 negative regulation of macrophage derived foam cell differentiation
Biological Process GO:0070527 platelet aggregation
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0033690 positive regulation of osteoblast proliferation
Biological Process GO:2000406 positive regulation of T cell migration
Biological Process GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0045124 regulation of bone resorption
Biological Process GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
Biological Process GO:0032880 regulation of protein localization
Biological Process GO:0051611 regulation of serotonin uptake
Biological Process GO:0014909 smooth muscle cell migration
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0046718 symbiont entry into host cell

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.