Search Results
Overview
| Uniprot ID | A0A5G2R7S2 |
|---|---|
| Protein Name | Endoplasmic reticulum resident protein 44 |
| Gene Name | ERP44 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 113 | YRGQRSVKALADYIR |
| 166 | RVFERVAKILHDDCT |
| 286 | FLHADCDKFRHPLLH |
| 296 | HPLLHIQKTPADCPV |
| 326 | RDVLIPGKLKQFVFD |
| 328 | VLIPGKLKQFVFDLH |
| 89 | AQRYRISKYPTLKLF |
Function
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum
Protein Sequence
10
MNPAVFLSLP
20
DLRCSLLLLV
30
TWVFTPVTPE
40
ITIYFFLCEE
50
CRFSQMLHPI
60
FEEASNVIKE
70
EYPNENQVVF
80
ARVDCDQHSD
90
IAQRYRISKY
100
PTLKLFRNGM
110
MMKREYRGQR
120
SVKALADYIR
130
QQKSDPIQEL
140
HDLAEITTLD
150
RSKRNIIGYF
160
EQKDSENYRV
170
FERVAKILHD
180
DCTFLSAFGA
190
VSKPERYSGD
200
NIVYKPPGHS
210
APDMVYLGYM
220
TNFDGTFNWI
230
QDKCVPLVRE
240
ITFENGEELT
250
EEGLPFLILF
260
HMKEDTESLE
270
IFQNEVARQL
280
ISEKGTINFL
290
HADCDKFRHP
300
LLHIQKTPAD
310
CPVIAIDSFR
320
HMYVFGDFRD
330
VLIPGKLKQF
340
VFDLHSGKLH
350
REFHHGPDPT
360
DTAPGQEVQD
370
VASSPPESSF
380
QKLAPSEYRY
TLLRDRDEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.