Search Results

Overview

Uniprot IDA0A5G2R805
Protein NameMitochondrial carrier homolog 1
Gene NameMTCH1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
232 QFVGREAKYSGVLSS

Function

Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. May play a role in apoptosis

Protein Sequence

10 MGASDPEVAP 20 WARGGAAGMA 30 GAGAGAGARG 40 GAAAGVEARA 50 RDPPPAHRAH 60 PRHPRPAAQP 70 SARRMDGASG 80 GLGSGDNAPT 90 TEALFVALGA 100 GVTALSHPLL 110 YVKLLIQVGH 120 EPMPPTIGTN 130 VLGRKVLYLP 140 SFFTYAKYIV 150 QVDGKIGLFR 160 GLSPRLMSNA 170 LSTVTRGSMK 180 KVFPPDEIEQ 190 VSNKDDMKTS 200 LKKVVKETSY 210 EMMMQCVSRM 220 LAHPLHVISM 230 RCMVQFVGRE 240 AKYSGVLSSI 250 GKIFKEEGLL 260 GFFVGLIPHL 270 LGDVVFLWGC 280 NLLAHFINAY 290 LVDDSVSDTP 300 GGLGNDQNPG 310 SQVGWNKDLS 320 IFPCTASIAV 330 SMLTYPFLLV 340 GDLMAVNNCG 350 LQAGLPPYSP 360 VFKSWIHCWK 370 YLSVQGQLFR 380 GSSLLFRRVS SGSCFALE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005741 mitochondrial outer membrane
Biological Process GO:0006915 apoptotic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.