Search Results
Overview
| Uniprot ID | A0A5G2R9A2 |
|---|---|
| Protein Name | Serine hydroxymethyltransferase |
| Gene Name | SHMT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 269 | VVTTTTHKTLRGARS |
| 329 | EYSLQVLKNARAMAD |
| 437 | EVKSKTTKLQDFKSF |
| 442 | TTKLQDFKSFLLKDP |
| 447 | DFKSFLLKDPETCRR |
| 92 | YSEGYPGKRYYGGAE |
Function
Interconversion of serine and glycine
Protein Sequence
10
PLWRCGQLVK
20
MAIRSQHSEA
30
AQTQTGEATK
40
GWSGQESLSD
50
SDPEMWELLR
60
REKDRQCRGL
70
ELIASENFCS
80
RAALEALGSC
90
LNNKYSEGYP
100
GKRYYGGAEV
110
VDEIELLCQR
120
RALEAFDLDP
130
AQWGVNVQPY
140
SGSPANLAAY
150
TALLQPHDRI
160
MGLDLPDGGH
170
LTHGYMTDVK
180
RISATSIFFE
190
SMPYKLNPKT
200
GLIDYDQLAL
210
TARLFRPRLI
220
IAGTSAYARL
230
IDYARMREVC
240
DEVKAHLLAD
250
MAHISGLVAA
260
KVIPSPFEHA
270
DVVTTTTHKT
280
LRGARSGLIF
290
YRKGVRTVDP
300
KTGREIPYTF
310
EDRINFAVFP
320
SLQGACTPMF
330
REYSLQVLKN
340
ARAMADALLE
350
RGYSLVSGGT
360
DNHLVLVDLR
370
PKGLDGARVE
380
RVLELVSITA
390
NKNTCPGDRS
400
AITPGGLRLG
410
TPALTSRQFR
420
EDDFRKVVAF
430
IDEGVSIGLE
440
VKSKTTKLQD
450
FKSFLLKDPE
460
TCRRLADLRQ
470
RVEQFARAFP
MPGFEEH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0070013 | intracellular organelle lumen |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004372 | glycine hydroxymethyltransferase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
| Biological Process | GO:0019264 | glycine biosynthetic process from L-serine |
| Biological Process | GO:0051289 | protein homotetramerization |
| Biological Process | GO:0006417 | regulation of translation |
| Biological Process | GO:0035999 | tetrahydrofolate interconversion |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.