Search Results
Overview
| Uniprot ID | A0A5G2R9D6 |
|---|---|
| Protein Name | Peroxiredoxin-5 |
| Gene Name | PRDX5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 18 | FEGEPEKKVNLAELF |
| 59 | VEQAEALKAKGIQVV |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events
Protein Sequence
10
VGDAIPSVVV
20
FEGEPEKKVN
30
LAELFKGKKG
40
VLFGVPGAFT
50
PGCSKTHLPG
60
FVEQAEALKA
70
KGIQVVACLS
80
VNDVFVTEMW
90
GRAHNTEGKV
100
RLLADPTGAF
110
GKETDLLLDD
120
SLVSLFGNRR
130
LKRFSMVIED
140
GIVKSLNVEP
150
DGTGLTCSLA
PNIISQL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005782 | peroxisomal matrix |
| Molecular Function | GO:0008379 | thioredoxin peroxidase activity |
| Biological Process | GO:0034599 | cellular response to oxidative stress |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.