Search Results
Overview
| Uniprot ID | A0A5G2RAB3 |
|---|---|
| Protein Name | Eukaryotic translation initiation factor 2A |
| Gene Name | EIF2A |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 190 | AVYVPGSKGAPSFVR |
| 348 | VWDVKNYKLISKPVA |
Function
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner
Protein Sequence
10
MVPSRILRGS
20
EGLYLVNGPP
30
HFTESTVFPR
40
YESGKNCKAY
50
TFSKDGTLFA
60
WGNGERINVI
70
NVTTKELLHS
80
FDLPKAVCLE
90
FSPKNTILAT
100
WQPYTTSKDG
110
AAGIPNLQLY
120
DMKTGTCLKS
130
FIQKKMQNWC
140
PSWSEDETLC
150
ARNVNNEVHF
160
FENNNFNTIA
170
NKLHLKKIND
180
FVLSPGPQPY
190
KVAVYVPGSK
200
GAPSFVRLYQ
210
YPNFDGPHAA
220
LANKSFFKAD
230
KVTMLWNKKA
240
TAVLVIASTE
250
VDKTGASYYG
260
EQTLHYIATN
270
GESAVVQLPK
280
NGPIYDVVWN
290
SSSTEFCAVY
300
GFMPAKATIF
310
NLKCDPVFDF
320
GTGPRNAAYY
330
SPHGHILVLA
340
GFGNLRGQME
350
VWDVKNYKLI
360
SKPVASDSTY
370
FAWCPDGEHI
380
LTATCAPRLR
390
VNNGYKIWHY
400
TGSVLHKYDV
410
PSNAELWQVS
420
WQPFLDGIFP
430
EKSITYQAVP
440
SDVPSEEPKV
450
ATAYRPPALR
460
NKPVTNSKLH
470
EEEPPQNMKP
480
QPGNEKPLSK
490
TALKNQRKHE
500
AKKAAKQEAR
510
SDKSPDMAPS
520
PAPQNTPRNT
530
VSHSTSGDPE
540
IDKKIKNLKK
550
KLKAIEQLKE
560
QAATGKQLEK
570
NQVCSAFFFF
580
FFLGPHLQHM
590
EVPSLGVESE
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005850 | eukaryotic translation initiation factor 2 complex |
| Molecular Function | GO:0043022 | ribosome binding |
| Molecular Function | GO:0003743 | translation initiation factor activity |
| Molecular Function | GO:0000049 | tRNA binding |
| Biological Process | GO:0006417 | regulation of translation |
| Biological Process | GO:0042255 | ribosome assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.